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| rdf:type
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| Description
| - Cerebrální venózní trombóza (CVT) představuje nebezpečné onemocnění s náročným diagnostickým algoritmem. Retrospektivně analyzujeme 8 případů CVT u skupiny mladých žen hospitalizovaných v období 18 měsíců mezi dubnem 2004 až říjnem 2005. U všech pacientek bylo provedeno vyšetření trombofilních markerů. Nejčastějším příznakem byla bolest hlavy (100 %), poruchy rovnováhy (87,5 %) a centrální hemiparéza nebo kvadruparéza (62,5 %). CT aMRI prokázaly venózní infarkt nebo venózní kongesci v (62,5 %), s petechiálním krvácením ve (25 %). Digitální subtrakční venografie potvrdila nejčastěji kombinaci okluzí sinus transversus a sigmoideus (75 %) a sinus sagitalis superior (62,5 %). Homozygotní forma mutace metylentetrahydrofolát reduktázy (MTHFR-C677T) byla zjištěna u 3 pacientek, 2 měly mutaci genu pro inhibitor aktivátoru plazminogenu (PAI-1) v homozygotní formě. CVT obvykle vzniká kombinací několika rizikových trombofilních faktorů. (cs)
- Cerebral venous thrombosis (CVT) is a dangerous disease with a difficult diagnosis. We present a retrospective analysis of 8 cases of CVT in young women who were hospitalised between April 2004 and October 2005. Thrombophilic markers were examined in all patients. The most common symptoms included headache (100%), vertigo (87.5%), hemiparesis or quadruparesis (62.5%). CT and MRI showed different types of parenchymal lesion infarction or vasogenic inflation in 62.50% and petechial haemorrhage in 25%. DSA venography confirmed the site of occlusion in the lateral and sigmoide sinus in 75%, and superior sagittal sinus (62.5%). We found 3 cases of the homozygous form of methylenetetrahydrofolate reductase (MTHFR-C677T), two patients had a plasminogen activator inhibitor-1 (PAI-1) homozygous mutation. Coexisting thrombophilic risk factors are usually involved in the onset of CVT.
- Cerebral venous thrombosis (CVT) is a dangerous disease with a difficult diagnosis. We present a retrospective analysis of 8 cases of CVT in young women who were hospitalised between April 2004 and October 2005. Thrombophilic markers were examined in all patients. The most common symptoms included headache (100%), vertigo (87.5%), hemiparesis or quadruparesis (62.5%). CT and MRI showed different types of parenchymal lesion infarction or vasogenic inflation in 62.50% and petechial haemorrhage in 25%. DSA venography confirmed the site of occlusion in the lateral and sigmoide sinus in 75%, and superior sagittal sinus (62.5%). We found 3 cases of the homozygous form of methylenetetrahydrofolate reductase (MTHFR-C677T), two patients had a plasminogen activator inhibitor-1 (PAI-1) homozygous mutation. Coexisting thrombophilic risk factors are usually involved in the onset of CVT. (en)
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| Title
| - Mozková žilní trombóza u uživatelek hormonální antikoncepce (cs)
- Cerebral venous thrombosis in oral contraceptive (OCP) users.
- Cerebral venous thrombosis in oral contraceptive (OCP) users. (en)
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| skos:prefLabel
| - Mozková žilní trombóza u uživatelek hormonální antikoncepce (cs)
- Cerebral venous thrombosis in oral contraceptive (OCP) users.
- Cerebral venous thrombosis in oral contraceptive (OCP) users. (en)
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| skos:notation
| - RIV/61989592:15110/07:00004269!RIV08-MSM-15110___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/07:00004269
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - cerebral venous thrombosis; thrombophilic markers; risk factors (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...i/riv/kodPristupu
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...telVyzkumneZpravy
| - The International Society on Thrombosis and Haemostasis
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Procházka, Martin
- Procházková, Jana
- Ľubušký, Marek
- Procházka, Vít
- Maděřič, D.
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| http://localhost/t...ganizacniJednotka
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