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| Description
| - Východisko: anemie po transplantaci ledviny (TL) je nezávislým rizikovým faktorem rozvoje hypertrofie levé komory srdeční a srdeční nedostatečnosti. Cílem studie bylo vyhodnocení prevalence anemie v období 6 měsíců až 5 let po TL a posouzení vztahu sérových koncentrací endogenního erytropoetinu (EPO) a funkce štěpu ke stupni úpravy chudokrevnosti. Metody: do souboru bylo zařazeno 140 nemocných po TL, 89 mužů (63,6%) a 51 žen (36,4%), průběrného věku 46,8?12,8 let. U všech jedinců byla vyšetřena koncentrace EPO a kreatininu (Kr) v séru, stanoveny hodnoty červené složky krevního obrazu (KO), sérové koncentrace feritinu (SF), plazmatická koncentrace želena (Fe), celková vazebná kapacita plazmy pro železo (CVK), saturace transferinu (ST), hodnoty kyseliny listové a vit. B12 v séru. Statistická analýza výsledků byla provedena lineární regresní analýzou, U testem a testem násobného rozpětí podle Duncana. Výsledky: normální hodnoty KO mělo 91 nemocných, mírný stupeň anemie s průběrnou hodnotou hemoglobinu (cs)
- Background/Aim: Although anemiais a common complication after renal transplantation (RT), data concerning endogenous erythropoietin (EPO) levels in long-term RT recipients are rare. The goal of this study was to evaluate the prevalence of anemia within 6 months to 5 years after RT and to assess the relationship between the serum concentrations of endogenous EPO, graft function and grade of improvement of anemia. Methods: 140 patients who had undergone RT were included in the group: 89 males (63.6%) and 51 females (36.4%), with an average age 46.8+-12.8 years. The serum concentrations of EPO and creatinine (Cr) were tested in all the individuals and the values of the red blood component of blood count, serum ferritin (SF), plasma iron concentration, plasma total iron-binding capacity (TIBC), transferrin saturation (TS), folic acid and vitamin B12 levels in the serum were determined. A statistical analysis of the results was performed using the correlation analysis, Mann-Whitney U test and Duncan´s mul
- Background/Aim: Although anemiais a common complication after renal transplantation (RT), data concerning endogenous erythropoietin (EPO) levels in long-term RT recipients are rare. The goal of this study was to evaluate the prevalence of anemia within 6 months to 5 years after RT and to assess the relationship between the serum concentrations of endogenous EPO, graft function and grade of improvement of anemia. Methods: 140 patients who had undergone RT were included in the group: 89 males (63.6%) and 51 females (36.4%), with an average age 46.8+-12.8 years. The serum concentrations of EPO and creatinine (Cr) were tested in all the individuals and the values of the red blood component of blood count, serum ferritin (SF), plasma iron concentration, plasma total iron-binding capacity (TIBC), transferrin saturation (TS), folic acid and vitamin B12 levels in the serum were determined. A statistical analysis of the results was performed using the correlation analysis, Mann-Whitney U test and Duncan´s mul (en)
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| Title
| - Endogenous erythropoietin levels and anemia in long-term renal transplant recipients
- Koncentrace endogenní erytropoetinu a anemia u nemocných po transplantaci ledviny (cs)
- Endogenous erythropoietin levels and anemia in long-term renal transplant recipients (en)
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| skos:prefLabel
| - Endogenous erythropoietin levels and anemia in long-term renal transplant recipients
- Koncentrace endogenní erytropoetinu a anemia u nemocných po transplantaci ledviny (cs)
- Endogenous erythropoietin levels and anemia in long-term renal transplant recipients (en)
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| skos:notation
| - RIV/61989592:15110/07:00004132!RIV08-MSM-15110___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/07:00004132
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Erythropoietin; renal transplantation; anemia; renal function; iron deficiency; immunosuppressive treatment (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - CH - Švýcarská konfederace
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Kidney and blood pressure research
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Hrubý, Miroslav
- Horák, Pavel
- Zadražil, Josef
- Zahálková, Jana
- Horčička, Vladko
- Štrebl, Pavel
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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