About: Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts

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About: Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	V současnosti představují invazivní kandidové infekce častou příčinu morbidity a mortality u pacientů hospitalizovaných se závažným onemocněním. Vzhledem k tomu, že přesná diagnóza kandidáz je stále obtížná, je rychlá a spolehlivá metoda na určování houbových patogenů důležitá při zahájení adekvátní antifungální terapie a(nebo při zavedení preventivních opatření. (cs) Currently, invasive candidal infections repressent an increasing cause of morbidity and mortality in seriously ill hospitalised patients. Because the accurate diagnosis of candidiasis remains difficult, a fast and reliable assay for characterization of fungal pathogens is critical for the early initiation of adequate antifungal therapy and/or for introduction of preventive measures. As novel molecular genetic techniques are continuously introduced, their role in the management of infectious diseases hal also been growing. Today, molecular strategies complement convetional methods and provide more accurate and detailed insight. It can be expected that future technical development will improve their potential furthemore. In this article, we providen a critical review on the value and limitations of molecular tools in pathogenic Candida species identification and strain typing regarding their sensitivity, discriminatory power, reproducibility, cost and ease of performance. Currently, invasive candidal infections repressent an increasing cause of morbidity and mortality in seriously ill hospitalised patients. Because the accurate diagnosis of candidiasis remains difficult, a fast and reliable assay for characterization of fungal pathogens is critical for the early initiation of adequate antifungal therapy and/or for introduction of preventive measures. As novel molecular genetic techniques are continuously introduced, their role in the management of infectious diseases hal also been growing. Today, molecular strategies complement convetional methods and provide more accurate and detailed insight. It can be expected that future technical development will improve their potential furthemore. In this article, we providen a critical review on the value and limitations of molecular tools in pathogenic Candida species identification and strain typing regarding their sensitivity, discriminatory power, reproducibility, cost and ease of performance. (en)
Title	Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts (en) Molekulárně-genetické přístupy v identifikaci a typizaci patogenních kvasinek rodu Candida (cs)
skos:prefLabel	Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts Molecular-genetic approaches to indentification and typing of pathogenic Candida yeasts (en) Molekulárně-genetické přístupy v identifikaci a typizaci patogenních kvasinek rodu Candida (cs)
skos:notation	RIV/61989592:15110/06:00003135!RIV07-MZ0-15110___
http://linked.open.../vavai/riv/strany	51-61
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR8365)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Raclavský, Vladislav Trtková, Jitka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	486638
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/06:00003135
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Candida; Infection; Typing; Mmolecular methods; PCR; Melting analysis (en)
http://linked.open.../riv/klicoveSlovo	Candida Typing PCR Infection Melting analysis Mmolecular methods
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[5C79555FA59B]
http://linked.open...i/riv/nazevZdroje	Biomedical Papers
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Pathogenic yeast species identification based on analysis of melting temperature of fingerprinting products
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	150
http://linked.open...iv/tvurceVysledku	Raclavský, Vladislav Trtková, Jitka
issn	1213-8118
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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