About: Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience     Goto   Sponge   NotDistinct   Permalink

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Description
  • U 122 nemocných s NHL po autologní transplantaci periferních krvetvorných buněk byla provedena retrospektivní univariační a multivariační analýza prognostických faktorů s ohledem na celkové přežití a přežití bez návratu onemocnění. Coxovou multivariační regresní analýzou byla potvrzena prognostická hodnota hladiny LDH před transplantací pro přežití bez návratu onemocnění a hladiny LDH a beta-2-mikroglobulinu před transplantací pro celkové přežití nemocných. Byla tak potvrzena vhodnost vyšetření těchto sérových markerů před provedením transplantace u nemocných s NHL. Supported by grant MSM 6198959205. (cs)
  • Several prognostic factors had been previously reported to be associated with overall and progression-free survival of patients with NHL after APSCT. We present a retrospective single center analysis with special attention to the markers that reflect the activity of disease at the time of transplantation. 122 patients with NHL indicated for APSCT for high-risk features at diagnosis partial response to first line treatment and/or relapse were included in the study. There were 66 women and 56 men at median age 45.5 years (range 19-66). 47 patients were with diagnosis of diffuse-large cell lymphoma, 34 with follicular lymphoma, 15 with mantle cell lymphoma and 26 patients had other lymphoma subtypes. Patients were transplanted in years 1997-2004. In all cases BEAM was used for conditioning. Median follow-up of patients was 27.0 months (range 3.0-93.9). 50 (41.0%) patients relapsed and 35 (28.7%) died. Age, stage of disease, IPI, bone marrow and extra-nodal involvement, presence of B symptoms and bulky di
  • Several prognostic factors had been previously reported to be associated with overall and progression-free survival of patients with NHL after APSCT. We present a retrospective single center analysis with special attention to the markers that reflect the activity of disease at the time of transplantation. 122 patients with NHL indicated for APSCT for high-risk features at diagnosis partial response to first line treatment and/or relapse were included in the study. There were 66 women and 56 men at median age 45.5 years (range 19-66). 47 patients were with diagnosis of diffuse-large cell lymphoma, 34 with follicular lymphoma, 15 with mantle cell lymphoma and 26 patients had other lymphoma subtypes. Patients were transplanted in years 1997-2004. In all cases BEAM was used for conditioning. Median follow-up of patients was 27.0 months (range 3.0-93.9). 50 (41.0%) patients relapsed and 35 (28.7%) died. Age, stage of disease, IPI, bone marrow and extra-nodal involvement, presence of B symptoms and bulky di (en)
Title
  • Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience
  • Prognostické faktory pro přežití pacientů s nehodgkinskými lymphomy (NHL) po autologní transplantaci krvetvorných buněk - nezávislá zkušenost centra (cs)
  • Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience (en)
skos:prefLabel
  • Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience
  • Prognostické faktory pro přežití pacientů s nehodgkinskými lymphomy (NHL) po autologní transplantaci krvetvorných buněk - nezávislá zkušenost centra (cs)
  • Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience (en)
skos:notation
  • RIV/61989592:15110/06:00002731!RIV07-MSM-15110___
http://linked.open.../vavai/riv/strany
  • 120
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6198959205)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 495278
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/06:00002731
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Non-Hodgkin´s lymphoma; autologous peripheral stem cell transplantation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [F30F97D04545]
http://linked.open...i/riv/nazevZdroje
  • Biology of Blood and Marrow Transplantation
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 12
http://linked.open...iv/tvurceVysledku
  • Faber, Edgar
  • Indrák, Karel
  • Raida, Luděk
  • Skoumalová, Ivana
  • Vondráková, Jana
  • Papajík, Tomáš
  • Zapletalová, J.
  • Marešová, Ivana
http://linked.open...n/vavai/riv/zamer
issn
  • 1083-8791
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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