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Description
| - dical scavenging and anti-lipoperoxidative effects of two organic fractions and two aqueous extracts from the leaves of a neglected Andean crop-yacon (Smallanthus sonchifolius Poepp. & Endl., Asteraceae) were determined using various in vitro models. The extracts' total phenolic content was 10.7-24.6%. They exhibited DPPH (IC50 16.14-33.39 microg/mL) and HO* scavenging activities (4.49-6.51 mg/mL). The extracts did not scavenge phenylglyoxylic ketyl radicals, but they retarded their formation. In the xanthine/xanthine oxidase superoxide radical generating system, the extracts' activities were 26.10-37.67 superoxide dismutase equivalents/mg. As one of the extracts displayed xanthine oxidase inhibitory activity, the effect of the extracts on a nonenzymatically generated superoxide was determined (IC50 7.36-21.01 microg/mL). The extracts inhibited t-butyl hydroperoxide-induced lipoperoxidation of microsomal and mitochondrial membranes (IC50 22.15-465.3 microg/mL). These results make yacon l
- dical scavenging and anti-lipoperoxidative effects of two organic fractions and two aqueous extracts from the leaves of a neglected Andean crop-yacon (Smallanthus sonchifolius Poepp. & Endl., Asteraceae) were determined using various in vitro models. The extracts' total phenolic content was 10.7-24.6%. They exhibited DPPH (IC50 16.14-33.39 microg/mL) and HO* scavenging activities (4.49-6.51 mg/mL). The extracts did not scavenge phenylglyoxylic ketyl radicals, but they retarded their formation. In the xanthine/xanthine oxidase superoxide radical generating system, the extracts' activities were 26.10-37.67 superoxide dismutase equivalents/mg. As one of the extracts displayed xanthine oxidase inhibitory activity, the effect of the extracts on a nonenzymatically generated superoxide was determined (IC50 7.36-21.01 microg/mL). The extracts inhibited t-butyl hydroperoxide-induced lipoperoxidation of microsomal and mitochondrial membranes (IC50 22.15-465.3 microg/mL). These results make yacon l (en)
- Byla studována schopnost dvou organických frakcí a dvou vodných extraktů z listů opomíjené andské plodiny jakonu (Smallanthus sonchifolius Poepp. & Endl, Asteraceae) zhášet volné radikály a inhibovat lipidovou peroxidaci v několika modelech in vitro. Celkový obsah fenolových látek v extraktech byl 10,7 - 24,6 %. Extrakty zhášely DPPH (IC50 16,14 - 33,39 µg/ml) a HO● (IC50 4,49 - 6,51 mg/ml). Nezhášely radikály kyseliny fenylglyoxylové, ale zpomalovaly jejich vznik. V systému xantin/xantinoxidasa, tvořícím superoxidový radikál, se aktivity extraktů pohybovaly v rozmezí 26,10 - 37,67 ekvivalentů superoxiddismutasy/mg. Vzhledem k tomu, že jeden z extraktů inhiboval xantinoxidasu, byl testován zhášecí efekt extraktů na superoxid tvořený neenzymatickou cestou (IC50 7,36 - 21,01 µg/ml). Extrakty inhibovaly lipidovou peroxidaci mikrosomálních a mitochondriálních membrán indukovanou terc-butylhydroperoxidem (IC50 22,15 - 465,3 µg/ml). Tyto výsledky podporují možné využití listů jakonu jako dopl (cs)
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Title
| - Radical scavenging and anti-lipoperoxidative activities of Smallanthus sonchifolius leaf extracts
- Radical scavenging and anti-lipoperoxidative activities of Smallanthus sonchifolius leaf extracts (en)
- Antiradikálová a antilipoperoxidační aktivita extraktů z listů Smallanthus sonchifolius. (cs)
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skos:prefLabel
| - Radical scavenging and anti-lipoperoxidative activities of Smallanthus sonchifolius leaf extracts
- Radical scavenging and anti-lipoperoxidative activities of Smallanthus sonchifolius leaf extracts (en)
- Antiradikálová a antilipoperoxidační aktivita extraktů z listů Smallanthus sonchifolius. (cs)
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skos:notation
| - RIV/61989592:15110/05:00001996!RIV06-MSM-15110___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/05:00001996
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Yacon; phenolic compounds; antioxidant activity; lipid peroxidation; protective effects (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Agricultural and Food Chemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Ulrichová, Jitka
- Valentová, Kateřina
- Šeršeň, František
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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