About: Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates

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About: Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Production of secreted aspartate proteinases was determined in a set of 646 isolates of Candida and non-Candida yeast species collected from 465 patients of the University Hospital in Olomouc (Czechia) in the period 1995-2002, and Candida samples obtained from 64 healthy volunteers using solid media developed for this purpose. Using random amplified polymorphic DNA analysis (RAPD) 79 Candida isolates from blood were analyzed to show potential relationships between clustering of the fingerprints and extracellular proteolytic activity of these strains. C. albicans, C. trapicalis and C. parapsilosis possess always proteolytic activity while non-Candida species did not display any proteolysis. A tight relationship between fingerprints and extracellular proteolysis in the Candida isolates was not shown. A remarkable consistency between fingerprint clusters and proteolysis occurred in a subset of C. parapsilosis samples. Suboptimal pH of the growth medium was shown to facilitate the investigation of potenti Production of secreted aspartate proteinases was determined in a set of 646 isolates of Candida and non-Candida yeast species collected from 465 patients of the University Hospital in Olomouc (Czechia) in the period 1995-2002, and Candida samples obtained from 64 healthy volunteers using solid media developed for this purpose. Using random amplified polymorphic DNA analysis (RAPD) 79 Candida isolates from blood were analyzed to show potential relationships between clustering of the fingerprints and extracellular proteolytic activity of these strains. C. albicans, C. trapicalis and C. parapsilosis possess always proteolytic activity while non-Candida species did not display any proteolysis. A tight relationship between fingerprints and extracellular proteolysis in the Candida isolates was not shown. A remarkable consistency between fingerprint clusters and proteolysis occurred in a subset of C. parapsilosis samples. Suboptimal pH of the growth medium was shown to facilitate the investigation of potenti (en) Byl sledován výskyt sekretované aspartát-proteinázy mezi klinickými izoláty. (cs)
Title	Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates (en) Sekretované aspartát-proteinázy, virulentní faktor Candia spp.: Výskyt mezi klinickými izoláty (cs)
skos:prefLabel	Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates Secreted aspartate proteinases, a virulence factor of Candida spp.: Occurrence among clinical isolates (en) Sekretované aspartát-proteinázy, virulentní faktor Candia spp.: Výskyt mezi klinickými izoláty (cs)
skos:notation	RIV/61989592:15110/04:00006293!RIV09-MZ0-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NI6485), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Hamal, Petr Raclavský, Vladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	585654
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/04:00006293
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ALBICANS; INFECTIONS; RESISTANCE; INHIBITION; FREQUENCY; TRACT; FUNGI; DNA (en)
http://linked.open.../riv/klicoveSlovo	INHIBITION DNA FREQUENCY TRACT FUNGI INFECTIONS RESISTANCE ALBICANS
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[5EAECB21B9BF]
http://linked.open...i/riv/nazevZdroje	Folia Microbiologica
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Pathogenic Candida strains: typing and characterization of secreted proteinases
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	49
http://linked.open...iv/tvurceVysledku	Hamal, Petr Dostál, J. Raclavský, Vladislav Pichová, I. Hrušková-Heidingsfeldová, O. Krylová, M.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0015-5632
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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