About: The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nádorový supresor PTEN blokuje buněčný cyklus na přechodu fáze G1-S u prostatických nádorových linií. Pro funkci PTEN v regulaci buněčného cyklu je nutná jeho fosfatázová aktivita. PTEN hraje důležitou úlohu v negativní regulaci PI3K/Akt dráhy. (cs) Phosphatase and tension homology deleted on chromosome ten (PTEN) is a tumor suppressor gene with protein and lipid phosphatase activity frequently altered in several types of human cancers. Herein, we demonstrate the effect of transfected wild type (wt) PTEN and its mutants (mt) L57W, H123Y, G129R that have lost lipid and protein phosphatase activity; and G129E characterized by loss of only lipid phosphatase activity, during the cell cycle and on apoptosis. Phosphatase and tension homology deleted on chromosome ten (PTEN) is a tumor suppressor gene with protein and lipid phosphatase activity frequently altered in several types of human cancers. Herein, we demonstrate the effect of transfected wild type (wt) PTEN and its mutants (mt) L57W, H123Y, G129R that have lost lipid and protein phosphatase activity; and G129E characterized by loss of only lipid phosphatase activity, during the cell cycle and on apoptosis. (en)
Title	The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines (en) Nádorový supresorový gen PTEN hraje úlohu v regulaci buněčného cyklu a apoptózy v prostatických nádorových linií. (cs)
skos:prefLabel	The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines (en) Nádorový supresorový gen PTEN hraje úlohu v regulaci buněčného cyklu a apoptózy v prostatických nádorových linií. (cs)
skos:notation	RIV/61989592:15110/04:00006054!RIV09-MZ0-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NC6779), Z(MSM 151100001)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Hlobilková, Alice Řiháková, Petra Knillová, Jana Pimrová, Eva KOLÁŘ, Zdeněk
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	590966
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/04:00006054
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PTEN/MMAC; phosphatase; cell cycle (en)
http://linked.open.../riv/klicoveSlovo	phosphatase cell cycle PTEN/MMAC
http://linked.open...ontrolniKodProRIV	[278017B521C1]
http://linked.open...i/riv/nazevZdroje	Hormonal Carcinogenesis - Proceeding of the 4th International Symposium
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...v/pocetStranKnihy	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of PTEN gene interactions in prostate cancer cell lines
http://linked.open...UplatneniVysledku	2004
http://linked.open...iv/tvurceVysledku	Kolář, Zdeněk Šváchová, Michaela Hlobilková, Alice Knillová, Jana Řiháková, Petra Guldberg, Per Pimrová, Eva
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20151100001
number of pages	7 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Springer-Verlag
https://schema.org/isbn	0-387-23783-6
http://localhost/t...ganizacniJednotka	15110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software