About: Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The purpose of the present study was to investigate clearance of selective cyclin-dependent kinase inhibitor roscovitine and to compare it with that of bohemine in mice in vivo. Clearence of roscovitine in mice was about four times slower than that of bohemine. Due to potential effects on the saturation of enzyme systems involved in the clearance, the in vivo study should be extended using high doses of the administered compounds. The purpose of the present study was to investigate clearance of selective cyclin-dependent kinase inhibitor roscovitine and to compare it with that of bohemine in mice in vivo. Clearence of roscovitine in mice was about four times slower than that of bohemine. Due to potential effects on the saturation of enzyme systems involved in the clearance, the in vivo study should be extended using high doses of the administered compounds. (en) Účelem práce bylo zkoumání clearance selektivního inhibitoru Cdk roscovitinu a s rovnání s boheminem u myší in vivo. (cs)
Title	Kyselina karboxylová je hlavním produktem biotransformace roscovitinu u myší in vivo. Srovnání s boheminem (cs) Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine (en)
skos:prefLabel	Kyselina karboxylová je hlavním produktem biotransformace roscovitinu u myší in vivo. Srovnání s boheminem (cs) Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine (en)
skos:notation	RIV/61989592:15110/03:00007296!RIV09-MSM-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OC B17.20), Z(MSM 151100001)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Veselý, Jaroslav Chmela, Zdeněk Rypka, Miroslav Lemr, Karel Riegrová, Dagmar
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	600361
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/03:00007296
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	carboxylic acid; roscovitine; biotransformation; mice; bohemine (en)
http://linked.open.../riv/klicoveSlovo	bohemine carboxylic acid roscovitine mice biotransformation
http://linked.open...ontrolniKodProRIV	[480FE6367548]
http://linked.open...i/riv/mistoVydani	Bologna, Italy
http://linked.open...i/riv/nazevZdroje	Cytochromes P450, Biochemistry, Biophysics and Drug Metabolism. 13th International Conference on Cytochromes P450
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20B17.20
http://linked.open...UplatneniVysledku	2003
http://linked.open...iv/tvurceVysledku	Lemr, Karel Veselý, Jaroslav Rypka, Miroslav Chmela, Zdeněk Riegrová, Dagmar Červenková, Kateřina
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20151100001
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Monduzzi Editore
https://schema.org/isbn	88-323-3141-1
http://localhost/t...ganizacniJednotka	15110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software