About: Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia     Goto   Sponge   NotDistinct   Permalink

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Description
  • Combination of miR-320b and miR-320a distinguished WM from HD with sensitivity of 85.7% and specificity of 94.4%, WM from IgM-MGUS with sensitivity of 90.5% and specificity of 73.3% and WM from IgM-MM with sensitivity of 81% and specificity of 100%. In WM, miR-320a was negatively associated with ?2-microglobulin and lymphoplasmacytic cells infiltration in the bone marrow. Further, miR-320a and miR-320b were predominantly present in the exosomal fraction of WM patients and were abundantly expressed in CD19+ and CD19- mononuclear cell fractions, with observed increase in CD19- cells. This article is protected by copyright. All rights reserved.
  • Combination of miR-320b and miR-320a distinguished WM from HD with sensitivity of 85.7% and specificity of 94.4%, WM from IgM-MGUS with sensitivity of 90.5% and specificity of 73.3% and WM from IgM-MM with sensitivity of 81% and specificity of 100%. In WM, miR-320a was negatively associated with ?2-microglobulin and lymphoplasmacytic cells infiltration in the bone marrow. Further, miR-320a and miR-320b were predominantly present in the exosomal fraction of WM patients and were abundantly expressed in CD19+ and CD19- mononuclear cell fractions, with observed increase in CD19- cells. This article is protected by copyright. All rights reserved. (en)
Title
  • Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia
  • Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia (en)
skos:prefLabel
  • Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia
  • Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia (en)
skos:notation
  • RIV/61988987:17110/15:A1501CD9!RIV15-MSM-17110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 71
http://linked.open...ai/riv/idVysledku
  • RIV/61988987:17110/15:A1501CD9
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • multiple myeloma; microRNA; monoclonal gammopathy of undetermined significance; Waldenstrom macroglobulinemia; qPCR (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [019B909320B5]
http://linked.open...i/riv/nazevZdroje
  • American Journal of Hematology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 90
http://linked.open...iv/tvurceVysledku
  • Hájek, Roman
  • Kryukov, Fedor
  • Minarik, Jiří
  • Almasi, Martina
  • Radova, Lenka
  • Adam, Zdenek
  • Besse, Lenka Kubiczkova
  • Krejci, Marta
  • Nekvindova, Jana
  • Pelcova, Jana
  • Pika, Tomas
  • Pikalova, Zuzana
  • Pour, Ludek
  • Scudla, Vlastimil
  • Sedlarikova, Lenka
  • Sevcikova, Sabina
issn
  • 1096-8652
number of pages
http://localhost/t...ganizacniJednotka
  • 17110
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