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  • Backround. Acute kidney injury (AKI) is a common serious complication of severe acute pancreatitis (SAP) and an important marker of morbidity and mortality in critically ill septic patients. AKI due to severe acute pancreatitis can be the result of hypoxemia, release of pancreatic amylase from the injured pancreas with impairment of renal microcirculation, decrease in renal perfusion pressure due to abdominal compartment syndrome, intraabdominal hypertension or hypovolemia. Endotoxins and reactive oxygen species (ROS) also play an important role in the pathophysiology of SAP and AKI. Knowledge of the pathophysiology and diagnosis of AKI following SAP might improve the therapeutic outcome of critically ill patients.
  • Backround. Acute kidney injury (AKI) is a common serious complication of severe acute pancreatitis (SAP) and an important marker of morbidity and mortality in critically ill septic patients. AKI due to severe acute pancreatitis can be the result of hypoxemia, release of pancreatic amylase from the injured pancreas with impairment of renal microcirculation, decrease in renal perfusion pressure due to abdominal compartment syndrome, intraabdominal hypertension or hypovolemia. Endotoxins and reactive oxygen species (ROS) also play an important role in the pathophysiology of SAP and AKI. Knowledge of the pathophysiology and diagnosis of AKI following SAP might improve the therapeutic outcome of critically ill patients. (en)
Title
  • Acute kidney injury following acute pancreatitis: A review
  • Acute kidney injury following acute pancreatitis: A review (en)
skos:prefLabel
  • Acute kidney injury following acute pancreatitis: A review
  • Acute kidney injury following acute pancreatitis: A review (en)
skos:notation
  • RIV/61988987:17110/13:A14019W5!RIV14-MSM-17110___
http://linked.open...avai/riv/aktivita
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  • 59432
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  • RIV/61988987:17110/13:A14019W5
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  • acute kidney injury; biomarkers; blood purification; intraabdominal hypertension; renal replacement therapy; multiple organ dysfunction syndrome; pathophysiology; severe acute pancreatitis; treatment options (en)
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  • CZ - Česká republika
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  • [F837166E5241]
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  • BIOMEDICAL PAPERS-OLOMOUC
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  • 157
http://linked.open...iv/tvurceVysledku
  • Martínek, Arnošt
  • Petejová, Naděžda
http://linked.open...ain/vavai/riv/wos
  • 000321737100003
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  • 1213-8118
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  • 17110
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