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  • BACKGROUND: Nodal involvement is one of the most significant prognostic factors in early-stage vulvar cancer. AIMS: To determine the diagnostic accuracy of sentinel lymph node (SLN) detection in early-stage vulvar cancer and to describe the characteristics of metastatic lymph node involvement. METHODS: Of 23 women with early-stage squamous cell vulvar cancer included in the study, five had lateral lesions and 18 had midline lesions. SLN detection was performed by using a radioactive tracer and blue dye, followed by radical vulvectomy or radical wide excision with uni/bilateral inguinofemoral lymphadenectomy, depending on tumour size and localization. SLNs were subsequently examined with haematoxylin-eosin and immunohistochemistry. CONCLUSION: The SLN biopsy performed by an experienced team is a feasible method, with high accuracy in patients with early-stage vulvar cancer. Prognostic value of micrometastases should be confirmed in further studies.
  • BACKGROUND: Nodal involvement is one of the most significant prognostic factors in early-stage vulvar cancer. AIMS: To determine the diagnostic accuracy of sentinel lymph node (SLN) detection in early-stage vulvar cancer and to describe the characteristics of metastatic lymph node involvement. METHODS: Of 23 women with early-stage squamous cell vulvar cancer included in the study, five had lateral lesions and 18 had midline lesions. SLN detection was performed by using a radioactive tracer and blue dye, followed by radical vulvectomy or radical wide excision with uni/bilateral inguinofemoral lymphadenectomy, depending on tumour size and localization. SLNs were subsequently examined with haematoxylin-eosin and immunohistochemistry. CONCLUSION: The SLN biopsy performed by an experienced team is a feasible method, with high accuracy in patients with early-stage vulvar cancer. Prognostic value of micrometastases should be confirmed in further studies. (en)
Title
  • Charakteristics of sentinel lymph nodes´metastatic involvement in early stage of vulvar cancer
  • Charakteristics of sentinel lymph nodes´metastatic involvement in early stage of vulvar cancer (en)
skos:prefLabel
  • Charakteristics of sentinel lymph nodes´metastatic involvement in early stage of vulvar cancer
  • Charakteristics of sentinel lymph nodes´metastatic involvement in early stage of vulvar cancer (en)
skos:notation
  • RIV/61988987:17110/09:A1100ZXU!RIV11-MSM-17110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 49
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 306817
http://linked.open...ai/riv/idVysledku
  • RIV/61988987:17110/09:A1100ZXU
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Carcinoma; Vulvar cancer; Biopsy; Metastatic lymph (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AU - Australské společenství
http://linked.open...ontrolniKodProRIV
  • [CA06BCD0443E]
http://linked.open...i/riv/nazevZdroje
  • AUST NZ J OBSTET GYN
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Procházka, M.
  • Kraft, Otakar
  • Šimetka, Ondřej
  • Ševčík, Libor
  • Klát, Jaroslav
  • Gráf, P.
  • Jalůvková, Z.
  • Waloschek, T.
issn
  • 0004-8666
number of pages
http://localhost/t...ganizacniJednotka
  • 17110
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