About: A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25     Goto   Sponge   NotDistinct   Permalink

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Description
  • Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by analysing 317,139 single- nucleotide polymorphisms in 1,989 lung cancer cases and 2,625 controls from six central European countries. We identified a locus in chromosome region 15q25 that was strongly associated with lung cancer ( P= 9 x 10(-10)).
  • Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by analysing 317,139 single- nucleotide polymorphisms in 1,989 lung cancer cases and 2,625 controls from six central European countries. We identified a locus in chromosome region 15q25 that was strongly associated with lung cancer ( P= 9 x 10(-10)). (en)
Title
  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 (en)
skos:prefLabel
  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 (en)
skos:notation
  • RIV/61988987:17110/08:A1000RSW!RIV10-MSM-17110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N, V
http://linked.open...iv/cisloPeriodika
  • 7187
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 354569
http://linked.open...ai/riv/idVysledku
  • RIV/61988987:17110/08:A1000RSW
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • FAGERSTROM TOLERANCE QUESTIONNAIRE; GENOME-WIDE ASSOCIATION; HAPLOTYPE MAP; DEPENDENCE; EXPRESSION; SMOKERS; CELLS; SNPS (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [F183DD0CC117]
http://linked.open...i/riv/nazevZdroje
  • NATURE
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http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 452
http://linked.open...iv/tvurceVysledku
  • Janout, Vladimír
  • Boffetta, P.
  • Fabianova, E.
  • Lissowska, J.
  • Mates, D.
  • Szeszenia-Dabrowska, N.
  • Zaridze, D.
  • Rudnai, P.
  • Hashibe, M.
  • Gaborieau, V.
  • Hung, R. J.
  • Foretová, L.
  • Bencko, V.
  • Mckay, J.
http://linked.open...ain/vavai/riv/wos
  • 000254567200046
issn
  • 0028-0836
number of pages
http://localhost/t...ganizacniJednotka
  • 17110
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