About: Brassinosteroids and their Biological Activities

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Brassinosteroids are endogenous plant polyhydroxysteroids that are essential for normal plant growth and development. They induce cell elongation and division, increase DNA and RNA polymerase activity, interact synergistically with auxins, stimulate ethylene production, and increase tolerance to temperature, water, and salinity stress. They are observed in many plant species and are present in nearly every part of the plant, although the highest concentrations occur in the reproductive organs. In mammalian cells, brassinosteroids inhibit cell growth and affect cell cycle progression; as such, they have potential for development as anticancer agents. Moreover, brassinosteroids and their synthetic derivatives possess antiangiogenic properties that could be effective in the treatment of any carcinoma. As such, they are an interesting source of lead compounds for developing novel natural product-derived anticancer drugs, and their properties have attracted the attention of many specialists in the fields of chemistry, biochemistry, pharmacology, plant physiology, and agriculture. Brassinosteroids are endogenous plant polyhydroxysteroids that are essential for normal plant growth and development. They induce cell elongation and division, increase DNA and RNA polymerase activity, interact synergistically with auxins, stimulate ethylene production, and increase tolerance to temperature, water, and salinity stress. They are observed in many plant species and are present in nearly every part of the plant, although the highest concentrations occur in the reproductive organs. In mammalian cells, brassinosteroids inhibit cell growth and affect cell cycle progression; as such, they have potential for development as anticancer agents. Moreover, brassinosteroids and their synthetic derivatives possess antiangiogenic properties that could be effective in the treatment of any carcinoma. As such, they are an interesting source of lead compounds for developing novel natural product-derived anticancer drugs, and their properties have attracted the attention of many specialists in the fields of chemistry, biochemistry, pharmacology, plant physiology, and agriculture. (en)
Title	Brassinosteroids and their Biological Activities Brassinosteroids and their Biological Activities (en)
skos:prefLabel	Brassinosteroids and their Biological Activities Brassinosteroids and their Biological Activities (en)
skos:notation	RIV/61389030:_____/13:00441336!RIV15-AV0-61389030
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED0007/01/01), P(IAA400550801)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Strnad, Miroslav Rárová, Lucie Oklešťková, Jana
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	63825
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/13:00441336
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Anticancer activity; apoptosis; bioassay (en)
http://linked.open.../riv/klicoveSlovo	bioassay apoptosis Anticancer activity
http://linked.open...ontrolniKodProRIV	[5493CCBED8F1]
http://linked.open...i/riv/mistoVydani	Heidelberg
http://linked.open...i/riv/nazevZdroje	Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...v/pocetStranKnihy	4242 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthesis of tritium labelled brassinosteroids and their application in the studies of their mechanism of action on molecular level. Centre of the Region Haná for Biotechnological and Agricultural Research
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Strnad, Miroslav Rárová, Lucie Oklešťková, Jana
number of pages	21 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/978-3-642-22144-6_174
http://purl.org/ne...btex#hasPublisher	Springer-Verlag
https://schema.org/isbn	978-3-642-22143-9

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