About: Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2524344/summary.html
Description	The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an - NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cycloalkyl, aryl, alkylcycloalkyl, arylalkyl, heterocycle, heterocyclealkyl, substituted alkyl, substituted cycloalkyl, substituted aryl, substituted arylalkyl, substituted heterocycle, substituted heteroaryl, substituted heteroarylalkyl, substituted heteroalkyl, substituted cycloalkyl alkyl and substituted cycloheteroalkyl alkyl, wherein the groups are preferably substituted by more than one halogen, hydroxyl, amino, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, alkyl, alkoxy, and substituted alkyl group. The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an - NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cycloalkyl, aryl, alkylcycloalkyl, arylalkyl, heterocycle, heterocyclealkyl, substituted alkyl, substituted cycloalkyl, substituted aryl, substituted arylalkyl, substituted heterocycle, substituted heteroaryl, substituted heteroarylalkyl, substituted heteroalkyl, substituted cycloalkyl alkyl and substituted cycloheteroalkyl alkyl, wherein the groups are preferably substituted by more than one halogen, hydroxyl, amino, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, alkyl, alkoxy, and substituted alkyl group. (en)
Title	Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use (en)
skos:prefLabel	Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use (en)
skos:notation	RIV/61389030:_____/12:00380690!RIV13-AV0-61389030
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/08/1649), Z(AV0Z50380511)
http://linked.open...cisloPatentuVzoru	CA2524344
http://linked.open...eleniPatentuVzoru	2012-03-13 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Havlíček, Libor Kryštof, Vladimír Strnad, Miroslav Lenobel, René Binarová, Pavla Moravcová, Daniela
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	163690
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/12:00380690
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pyrazolo[4,3-D]pyrimidines; preparation; methods of use (en)
http://linked.open.../riv/klicoveSlovo	3-D]pyrimidines methods of use preparation Pyrazolo[4
http://linked.open...ontrolniKodProRIV	[EE5C2BBC1FA5]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Gatineau, Québec
http://linked.open...atelePatentuVzoru	Canadian Intellectual Property Office (CIPO)
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Modulation of cell division of normal and cancer cells by cyclin-dependent kinase inhibitors
http://linked.open...UplatneniVysledku	2012
http://linked.open...ydaniPatentuVzoru	CA - Kanada
http://linked.open...iv/tvurceVysledku	Binarová, Pavla Havlíček, Libor Kryštof, Vladimír Schmülling, T. Strnad, Miroslav Lenobel, René Uldrijan, S. Mlejnek, P. Moravcová, Daniela Vojtěšek, B.
http://linked.open...mniOchranaPatentu	D - Národní patentový úřad mimo ČR
http://linked.open...avai/riv/vlastnik	Ústav experimentální botaniky AV ČR, v. v. i - Univerzita Palackého v Olomouci
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	B - Využívaný třetí stranou na základě licenční smlouvy
http://linked.open...n/vavai/riv/zamer	Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy
http://linked.open...stnikPatentuVzoru	Ústav experimentální botaniky AV ČR, v. v. i - Univerzita Palackého v Olomouci

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 25 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software