About: N9-substituted derivatives of kinetin: Effective anti-senescence agents

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The first isolated cytokinin, 6-furfurylaminopurine (kinetin or Kin), was identified almost 55 years ago. Its biological effects on plant cells and tissues include influences on such processes as gene expression, cell cycle, chloroplast development, chlorophyll biosynthesis, stimulation of vascular development, delay of senescence, and mobilization of nutrients. In the present study we prepared a series of eight N9-substituted Kin derivatives, and characterized them with available physicochemical methods such as Cl+ mass spectrometry and (1)H NMR spectroscopy. All compounds were tested in three classical cytokinin bioassays: a tobacco callus assay, an Amaranthus assay, and a senescence assay with excised wheat leaves. The ability of the compounds to interact with Arabidopsis cytokinin receptors CRE1/AHK4 and AHK3 was tested in a bacterial receptor assay. The first isolated cytokinin, 6-furfurylaminopurine (kinetin or Kin), was identified almost 55 years ago. Its biological effects on plant cells and tissues include influences on such processes as gene expression, cell cycle, chloroplast development, chlorophyll biosynthesis, stimulation of vascular development, delay of senescence, and mobilization of nutrients. In the present study we prepared a series of eight N9-substituted Kin derivatives, and characterized them with available physicochemical methods such as Cl+ mass spectrometry and (1)H NMR spectroscopy. All compounds were tested in three classical cytokinin bioassays: a tobacco callus assay, an Amaranthus assay, and a senescence assay with excised wheat leaves. The ability of the compounds to interact with Arabidopsis cytokinin receptors CRE1/AHK4 and AHK3 was tested in a bacterial receptor assay. (en)
Title	N9-substituted derivatives of kinetin: Effective anti-senescence agents N9-substituted derivatives of kinetin: Effective anti-senescence agents (en)
skos:prefLabel	N9-substituted derivatives of kinetin: Effective anti-senescence agents N9-substituted derivatives of kinetin: Effective anti-senescence agents (en)
skos:notation	RIV/61389030:_____/11:00368599!RIV12-AV0-61389030
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED0007/01/01), P(GA301/08/1649), P(GA522/09/1576), P(GAP501/10/1450), P(LC06034), Z(AV0Z50380511), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Spíchal, Lukáš Gruz, Jiří Zatloukal, Marek Doležal, Karel Strnad, Miroslav Galuszka, Petr Szüčová, Lucie Nisler, Jaroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	216918
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/11:00368599
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cytokinin derivatives; Synthesis; Cytokinin activity; Senescence; Membrane damage (en)
http://linked.open.../riv/klicoveSlovo	Synthesis Senescence Cytokinin activity Cytokinin derivatives Membrane damage
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[809D6B1AD162]
http://linked.open...i/riv/nazevZdroje	Phytochemistry
http://linked.open...in/vavai/riv/obor	EF
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Regulation of morphogenesis of plant cells and organs Centre of the Region Haná for Biotechnological and Agricultural Research Modulation of cell division of normal and cancer cells by cyclin-dependent kinase inhibitors Development of biospecific ligands for affinity chromatography of cytokinin related proteins. Fluorescently labeled cytokinins as the way to understand their action in plants
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	72
http://linked.open...iv/tvurceVysledku	Doležal, Karel Gruz, Jiří Strnad, Miroslav Spíchal, Lukáš Zatloukal, Marek Galuszka, Petr Šmehilová, M. Mik, V. Nisler, Jaroslav Szüčová, Lucie
http://linked.open...ain/vavai/riv/wos	000290505500020
http://linked.open...n/vavai/riv/zamer	Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0031-9422
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.phytochem.2011.02.002

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