About: Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	L'invention concerne à 3 -, 5 -,7-pyrazolo trisubstitués (4,3-d) pyrimidines représenté par la formule générale (I), et alkyle, cycloalkyle, cyclohétéroalkyle, cycloalkyle, alkyle, aryle ou alkylaryle, R5 est halogène,-NHNH2,-NHOH, NHCONH2, guanylo (NH-C (NH) NH2) éventuellement substitué C1-C6 alkyle, alcényle, alcynyle, cycloalkyle en C3-C15, Rf (cycloalkyle en C3-C15), un hétérocycle, hétéroalkyle, aryle , hétéroaryle, arylalkyle, cyclohétéroalkyle, alkyle cyclohétéroalkyle, hétéroarylalkyle groupe etc.Cette invention concerne de nouveaux pyrazolo (4,3-d) pyrimidine et leur utilisation dans les services publics appropriés, en particulier les méthodes diagnostiques et thérapeutiques. Plus précisément, la présente invention concerne également l'utilisation du 3,5,7-pyrazolo trisubstitués (4,3-d) pyrimidines ou un sel pharmaceutiquement acceptable de celui-ci en combinaison avec des cytostatiques dans la préparation d'un médicament pour traiter le cancer. The invention relates to 3-,5-,7-trisubstituted pyrazolo(4,3-d)pyrimidines represented by the general formula (I), and substituted alkyl, cycloalkyl, cycloheteroalkyl, cycloalkyl, alkyl, aryl or alkylaryl group, R5 is halogen, -NHNH2, -NHOH, NHCONH2, guanylo (NH-C(NH)NH2) an optionally substituted C1-C6 alkyl, alkenyl, alkinyl, C3-C15 cycloalkyl, Rf (C3-C15 cycloalkyl), heterocycle, heteroalkyl, aryl, heteroaryl, arylalkyl, cycloheteroalkyl, cycloheteroalkyl alkyl, heteroarylalkyl group etc.This invention relates to new pyrazolo(4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. More specifically, the present invention also relates to the use of 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines or a pharmaceutically acceptable salt thereof in combination with cytostatics in the preparation of a medicament for treating cancer. (en)
Title	Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy (en)
skos:prefLabel	Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy (en)
skos:notation	RIV/61389030:_____/10:00352738!RIV11-GA0-61389030
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA301/08/1649), P(GA522/09/1576)
http://linked.open...cisloPatentuVzoru	CA2480409
http://linked.open...eleniPatentuVzoru	2010-06-22 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Havlíček, Libor Kryštof, Vladimír Strnad, Miroslav Lenobel, René Moravcová, Daniela
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	275179
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/10:00352738
http://linked.open...riv/jazykVysledku	fre - francouzština
http://linked.open.../riv/klicovaSlova	novel pyrazolo[4,3-D]pyrimidines; process; preparation; method; therapy (en)
http://linked.open.../riv/klicoveSlovo	method therapy 3-D]pyrimidines process preparation novel pyrazolo[4
http://linked.open...ontrolniKodProRIV	[07A1E6EA1DC4]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Ottawa
http://linked.open...atelePatentuVzoru	Canadian Intellectual Property Office http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2480409/summary.html?type=number_search
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Modulation of cell division of normal and cancer cells by cyclin-dependent kinase inhibitors Development of biospecific ligands for affinity chromatography of cytokinin related proteins.
http://linked.open...UplatneniVysledku	2010
http://linked.open...ydaniPatentuVzoru	CA - Kanada
http://linked.open...iv/tvurceVysledku	Havlíček, Libor Kryštof, Vladimír Strnad, Miroslav Lenobel, René Moravcová, Daniela
http://linked.open...mniOchranaPatentu	D - Národní patentový úřad mimo ČR
http://linked.open...avai/riv/vlastnik	Ústav experimentální botaniky AV ČR, v. v. i., Univerzita Palackého v Olomouci
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	B - Využívaný třetí stranou na základě licenční smlouvy
http://linked.open...stnikPatentuVzoru	Ústav experimentální botaniky AV ČR, v. v. i., Univerzita Palackého v Olomouci

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 25 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software