About: Steroid conjugates: Synthesis and preliminary biological testing of pro-juvenoids

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A series of 10 new pro-juvenoids (juvenogens, insect hormonogenic compounds, pro-drug-like agents) was synthesized using isomeric synthetic juvenoids (insect juvenile hormone analogs) and steroid molecules as patterns modifying parts of the complex hormonogenic molecules. In addition, several new synthons were prepared, which were required by the designed synthetic protocol to achieve the target molecules. These pro-juvenoids were subjected to the topical screening tests and to the drinking assays on the red firebug (Pyrrhocoris apterus), a convenient model laboratory phytophagous insect. Simple and efficient synthetic procedures for the preparation of the target pro-juvenoids and their synthons are presented. Furthermore, the biological activity of the pro-juvenoids in comparison with the activity of their parent juvenoids and that of several commercially available agents is demonstrated. A series of 10 new pro-juvenoids (juvenogens, insect hormonogenic compounds, pro-drug-like agents) was synthesized using isomeric synthetic juvenoids (insect juvenile hormone analogs) and steroid molecules as patterns modifying parts of the complex hormonogenic molecules. In addition, several new synthons were prepared, which were required by the designed synthetic protocol to achieve the target molecules. These pro-juvenoids were subjected to the topical screening tests and to the drinking assays on the red firebug (Pyrrhocoris apterus), a convenient model laboratory phytophagous insect. Simple and efficient synthetic procedures for the preparation of the target pro-juvenoids and their synthons are presented. Furthermore, the biological activity of the pro-juvenoids in comparison with the activity of their parent juvenoids and that of several commercially available agents is demonstrated. (en)
Title	Steroid conjugates: Synthesis and preliminary biological testing of pro-juvenoids Steroid conjugates: Synthesis and preliminary biological testing of pro-juvenoids (en)
skos:prefLabel	Steroid conjugates: Synthesis and preliminary biological testing of pro-juvenoids Steroid conjugates: Synthesis and preliminary biological testing of pro-juvenoids (en)
skos:notation	RIV/61389030:_____/10:00349942!RIV11-MSM-61389030
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(2B06024), Z(AV0Z40550506), Z(AV0Z50380511), Z(MSM6046070901), Z(MSM6046137305)
http://linked.open...iv/cisloPeriodika	23
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Wimmer, Zdeněk Pavlík, Milan Ryšavá, Hana Svobodová, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	290099
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/10:00349942
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pyrrhocoris apterus; Structure–activity relationship; Juvenoid (en)
http://linked.open.../riv/klicoveSlovo	Pyrrhocoris apterus Juvenoid Structure–activity relationship
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[28EE0D4EE591]
http://linked.open...i/riv/nazevZdroje	Bioorganic & Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Supramolecular materials based on natural phytosterols for application in biology
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Svobodová, Hana Wimmer, Zdeněk Šaman, David Pavlík, Milan Drašar, Pavel Ryšavá, Hana
http://linked.open...ain/vavai/riv/wos	000284059500008
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy Setrvalé zemědělství, kvalita zemědělské produkce, krajinné a přírodní zdroje. Teoretické základy potravinářských a biochemických technologií
issn	0968-0896
number of pages	10 (xsd:int)

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