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  • Polyamines are ubiquitous compounds, which are involved in crucial physiological events including cell growth and differentiation. The catabolic oxidative degradation of polyamines is catalyzed by quinoprotein copper-containing amine oxidases (CAOs) and flavoprotein polyamine oxidases (PAOs). Various synthetic polyamine analogs and polyamine derivatives have been reported, which represent important tools (substrates or inhibitors) in the study of catalytic properties of the enzymes. In this work, two related compounds were studied in the reactions with plant amine oxidases: 1,8-diamino-3,6-dioxaoctane (DADO) and 1,10-bis(2pyridinylmethyl)-4,7-dioxa-1,10-diazadecane (BPDD). Based on activity and stoichiometry assays together with spectrophotometric measurements, DADO can be considered a good substrate for grass pea, lentil and E. characias CAOs with K-m values in the range 10(-4) - 10(-3) M. Its oxidative degradation produces the corresponding aminoaldehyde 1,8-amino-3,6-dioxaoctanal,which does not ...
  • Polyamines are ubiquitous compounds, which are involved in crucial physiological events including cell growth and differentiation. The catabolic oxidative degradation of polyamines is catalyzed by quinoprotein copper-containing amine oxidases (CAOs) and flavoprotein polyamine oxidases (PAOs). Various synthetic polyamine analogs and polyamine derivatives have been reported, which represent important tools (substrates or inhibitors) in the study of catalytic properties of the enzymes. In this work, two related compounds were studied in the reactions with plant amine oxidases: 1,8-diamino-3,6-dioxaoctane (DADO) and 1,10-bis(2pyridinylmethyl)-4,7-dioxa-1,10-diazadecane (BPDD). Based on activity and stoichiometry assays together with spectrophotometric measurements, DADO can be considered a good substrate for grass pea, lentil and E. characias CAOs with K-m values in the range 10(-4) - 10(-3) M. Its oxidative degradation produces the corresponding aminoaldehyde 1,8-amino-3,6-dioxaoctanal,which does not ... (en)
  • Interaction of plant amine oxidases with diaminoethers. (cs)
Title
  • Interaction of plant amine oxidases with diaminoethers
  • Interaction of plant amine oxidases with diaminoethers (en)
  • Interaction of plant amine oxidases with diaminoethers (cs)
skos:prefLabel
  • Interaction of plant amine oxidases with diaminoethers
  • Interaction of plant amine oxidases with diaminoethers (en)
  • Interaction of plant amine oxidases with diaminoethers (cs)
skos:notation
  • RIV/61389030:_____/07:00305982!RIV08-AV0-61389030
http://linked.open.../vavai/riv/strany
  • 222;232
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50380511), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • -
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 427059
http://linked.open...ai/riv/idVysledku
  • RIV/61389030:_____/07:00305982
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • diamine oxidase; diaminoether; inhibition (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [817397323D44]
http://linked.open...i/riv/nazevZdroje
  • Arkivoc
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • Part 7
http://linked.open...iv/tvurceVysledku
  • Šebela, M.
  • Lenobel, René
  • Peč, P.
  • Floris, G.
  • Jarkovská, K.
  • Medda, R.
  • Padiglia, A.
http://linked.open...n/vavai/riv/zamer
issn
  • 1424-6376
number of pages
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