About: Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cytokinin activity of forty-eight 6-benzyladenosine derivatives at both the receptor and cellular levels as well as their anticancer properties were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine riboside with corresponding substituted benzylamines and characterized by standard collection of physico-chemical methods. The majority of synthesized derivatives exhibited high activity in all three of the cytokinin bioassays used (tobacco callus, wheat leaf senescence and Amaranthus bioassay). The highest activities were observed in the senescence bioassay. For several of the compounds tested, significant differences in activity were found between the bioassays used, indicating that diverse recognition systems may operate. This suggests that it may be possible to modulate particular cytokinin-dependent processes with specific compounds. In contrast to their high activity in bioassays, the tested compounds were recognized with only very low sensitivi... Cytokinin activity of forty-eight 6-benzyladenosine derivatives at both the receptor and cellular levels as well as their anticancer properties were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine riboside with corresponding substituted benzylamines and characterized by standard collection of physico-chemical methods. The majority of synthesized derivatives exhibited high activity in all three of the cytokinin bioassays used (tobacco callus, wheat leaf senescence and Amaranthus bioassay). The highest activities were observed in the senescence bioassay. For several of the compounds tested, significant differences in activity were found between the bioassays used, indicating that diverse recognition systems may operate. This suggests that it may be possible to modulate particular cytokinin-dependent processes with specific compounds. In contrast to their high activity in bioassays, the tested compounds were recognized with only very low sensitivi... (en) Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines. (cs)
Title	Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines (en) Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines (cs)
skos:prefLabel	Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines (en) Preparation, biological activity and endogenous occurrence of N-6-benzyladenosines (cs)
skos:notation	RIV/61389030:_____/07:00305966!RIV08-AV0-61389030
http://linked.open.../vavai/riv/strany	3737;3747
http://linked.open...avai/riv/aktivita	P S V Z
http://linked.open...avai/riv/aktivity	P(GA206/07/0570), P(GA522/06/0108), S, V, Z(AV0Z50380511), Z(MSM6198959216), Z(MSM6198959218)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Spíchal, Lukáš Voller, Jiří Kryštof, Vladimír Doležal, Karel Hényková, Eva Novák, Ondřej Strnad, Miroslav Popa, Igor Holub, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	443844
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/07:00305966
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N-6-benzyladenosine; cytokinin; receptor (en)
http://linked.open.../riv/klicoveSlovo	cytokinin receptor N-6-benzyladenosine
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[9BA2BD50BF24]
http://linked.open...i/riv/nazevZdroje	Bioorganic & Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	New cytokinin derivatives in plants: isolation, identification and biological activity Influence of new 6-benzylaminopurine derivatives on micropropagation of selected broad-leaved forest tree species
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	15
http://linked.open...iv/tvurceVysledku	Doležal, Karel Holub, Jan Kryštof, Vladimír Novák, Ondřej Strnad, Miroslav Spíchal, Lukáš Voller, Jiří Popa, Igor Hauserová, Eva Chakrabarty, K.
http://linked.open...n/vavai/riv/zamer	Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy Modulation of signalling and regulatory pathways in normal and cancer cells Komplexní sloučeniny a oxidy přechodných kovů s využitím v bioaplikacích a nanotechnologiích
issn	0968-0896
number of pages	11 (xsd:int)

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