About: Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds

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About: Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://rustreg.upol.cz/patents/06_heterocycl_comp/udelene_patenty/NZ_538597.pdf
Description	Disclosed is a pharmaceutical composition which contains a heterocyclic compound based on N6-substituted adenine of the general formula I wherein: R2 is a H, halogen, hydroxyl, alkoxy, amino, hydrazo, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, cycloalkyl or carbamoyl group; R6 is R6'-X; X is -NH- R6' is substituted phenyl or substituted benzyl. The disclosed composition is for use as a mitotic or antimitotic compound expecially for treating cancer, psoriasis, rheumatoid arthritis, lupus, type I diabetes, multiple sclerosis, restenosis, polycystic kidney disease, graft rejection, graft versus host disease, gout, parasitoses and Alzheimers disease among others. Disclosed is a pharmaceutical composition which contains a heterocyclic compound based on N6-substituted adenine of the general formula I wherein: R2 is a H, halogen, hydroxyl, alkoxy, amino, hydrazo, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, cycloalkyl or carbamoyl group; R6 is R6'-X; X is -NH- R6' is substituted phenyl or substituted benzyl. The disclosed composition is for use as a mitotic or antimitotic compound expecially for treating cancer, psoriasis, rheumatoid arthritis, lupus, type I diabetes, multiple sclerosis, restenosis, polycystic kidney disease, graft rejection, graft versus host disease, gout, parasitoses and Alzheimers disease among others. (en)
Title	Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds (en)
skos:prefLabel	Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds Heterocyclic compound based on N6-substituted adenine, methods of their preparation, their use for preparation of drugs and pharmaceutical preparations containing these compounds (en)
skos:notation	RIV/61389030:_____/07:00090753!RIV12-AV0-61389030
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA206/07/0570), P(GA522/06/0108), Z(AV0Z50380511)
http://linked.open...cisloPatentuVzoru	NZ538597
http://linked.open...eleniPatentuVzoru	2007-01-11 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Zatloukal, Marek Doležal, Karel Strnad, Miroslav Popa, Igor Holub, Jan Lenobel, René
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	424025
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/07:00090753
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adenine; cytokinins; cytotoxicity (en)
http://linked.open.../riv/klicoveSlovo	cytotoxicity adenine cytokinins
http://linked.open...ontrolniKodProRIV	[93F74C85A90A]
http://linked.open.../licencniPoplatek	N - Poskytovatel licence na výsledek nepožaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Wellington
http://linked.open...atelePatentuVzoru	Intellectual Property Office of New Zealand (IPONZ)
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	New cytokinin derivatives in plants: isolation, identification and biological activity Influence of new 6-benzylaminopurine derivatives on micropropagation of selected broad-leaved forest tree species
http://linked.open...UplatneniVysledku	2007
http://linked.open...ydaniPatentuVzoru	NZ - Nový Zéland
http://linked.open...iv/tvurceVysledku	Doležal, Karel Holub, Jan Strnad, Miroslav Zatloukal, Marek Popa, Igor Lenobel, René Werbrouck, S.
http://linked.open...mniOchranaPatentu	D - Národní patentový úřad mimo ČR
http://linked.open...avai/riv/vlastnik	Ústav experimentální botaniky AVČR, v. v. i.
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	B - Využívaný třetí stranou na základě licenční smlouvy
http://linked.open...n/vavai/riv/zamer	Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy
http://linked.open...stnikPatentuVzoru	Ústav experimentální botaniky AVČR, v. v. i.

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