About: PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an -NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cy... The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an -NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cy... (en) PYRAZOLO [4, 3-D]PYRIMIDINEY, ZPŮSOBY JEJICH PŘÍPRAVY A METODY POUŽITÍ (cs)
Title	PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE (en) PYRAZOLO [4, 3-D]PYRIMIDINEY, ZPŮSOBY JEJICH PŘÍPRAVY A METODY POUŽITÍ (cs)
skos:prefLabel	PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE (en) PYRAZOLO [4, 3-D]PYRIMIDINEY, ZPŮSOBY JEJICH PŘÍPRAVY A METODY POUŽITÍ (cs)
skos:notation	RIV/61389030:_____/04:00000304!RIV/2005/AV0/A56005/N
http://linked.open...tracePatentuVzoru	2004-04-05 (xsd:date)
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z5038910), Z(MSM 153100008)
http://linked.open...cisloPatentuVzoru	WO2004098608
http://linked.open...eleniPatentuVzoru	2004-12-12 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Havlíček, Libor Kryštof, Vladimír Strnad, Miroslav Lenobel, René Binarová, Pavla Moravcová, Daniela
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální botaniky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	583269
http://linked.open...ai/riv/idVysledku	RIV/61389030:_____/04:00000304
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pyrimidine; anticancer drug (en)
http://linked.open.../riv/klicoveSlovo	anticancer drug pyrimidine
http://linked.open...ontrolniKodProRIV	[854CD445A90D]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	München
http://linked.open...atelePatentuVzoru	European Patent Office
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...ydaniPatentuVzoru	DE - Spolková republika Německo
http://linked.open...iv/tvurceVysledku	Binarová, Pavla Havlíček, Libor Kryštof, Vladimír Schmülling, T. Strnad, Miroslav Lenobel, René Uldrijan, S. Mlejnek, P. Moravcová, Daniela Vojtěšek, B.
http://linked.open...avai/riv/vlastnik	Ústav experimentální botaniky AV ČR
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...n/vavai/riv/zamer	Physiological and genetical bases of plant development, cell cycle, morphogenesis, stress reactions and biotechnologies. Genome organisation and function http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20153100008
http://linked.open...stnikPatentuVzoru	Ústav experimentální botaniky AV ČR

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