About: Focused tandem shock waves in water and their potential application in cancer treatment

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 µs have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPa followed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW. Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 µs have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPa followed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW. (en)
Title	Focused tandem shock waves in water and their potential application in cancer treatment Focused tandem shock waves in water and their potential application in cancer treatment (en)
skos:prefLabel	Focused tandem shock waves in water and their potential application in cancer treatment Focused tandem shock waves in water and their potential application in cancer treatment (en)
skos:notation	RIV/61389021:_____/11:00369995!RIV12-AV0-61389021
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA202/09/1151), Z(AV0Z20430508)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Šunka, Pavel Hoffer, Petr Lukeš, Petr Stelmashuk, Vitaliy
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyziky plazmatu AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	200049
http://linked.open...ai/riv/idVysledku	RIV/61389021:_____/11:00369995
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	focused shock waves; underwater discharge; cancer treatment (en)
http://linked.open.../riv/klicoveSlovo	cancer treatment focused shock waves underwater discharge
http://linked.open...ontrolniKodProRIV	[E7B8FD1C44DE]
http://linked.open...v/mistoKonaniAkce	Manchester
http://linked.open...i/riv/mistoVydani	Manchester
http://linked.open...i/riv/nazevZdroje	Proceedings of 28th International Symposium on Shock Waves
http://linked.open...in/vavai/riv/obor	BL
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Focused tandem shock waves and their potential application in cancer treatment and controlled drug delivery
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Hoffer, Petr Lukeš, Petr Poučková, P. Stelmashuk, Vitaliy Šunka, Pavel Beneš, J. Zeman, J. Binder, S. Dibdiak, L. Kolářová, H. Tománková, K.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2011-07-17 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Physical and chemical processes in plasmas and theis applications
number of pages	6 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Springer-Verlag
https://schema.org/isbn	978-3-642-25687-5

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