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rdf:type
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Description
| - In this contribution the ability of 19F MAS NMR spectroscopy to probe structural variability of poorly water-soluble drugs formulated as solid dispersions in polymer matrices is discussed. The application potentiality of the proposed approach is demonstrated on a moderately sized active pharmaceutical ingredient (API, Atorvastatin) exhibiting extensive polymorphism. In this respect, a range of model systems with the API incorporated in the matrix of polvinylpyrrolidone (PVP) was prepared.
- In this contribution the ability of 19F MAS NMR spectroscopy to probe structural variability of poorly water-soluble drugs formulated as solid dispersions in polymer matrices is discussed. The application potentiality of the proposed approach is demonstrated on a moderately sized active pharmaceutical ingredient (API, Atorvastatin) exhibiting extensive polymorphism. In this respect, a range of model systems with the API incorporated in the matrix of polvinylpyrrolidone (PVP) was prepared. (en)
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Title
| - Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis
- Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis (en)
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skos:prefLabel
| - Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis
- Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis (en)
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skos:notation
| - RIV/61389013:_____/13:00383512!RIV13-AV0-61389013
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(2B08021), P(GPP106/11/P426), Z(AV0Z40500505)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61389013:_____/13:00383512
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - solid-state NMR; factor analysis; 19F MAS NMR (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Urbanová, Martina
- Šeděnková, Ivana
- Brus, Jiří
- Kobera, Libor
- Policianová, Olivia
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.saa.2012.02.057
|