About: Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells     Goto   Sponge   NotDistinct   Permalink

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Description
  • Poly(N-vinylpyrrolidone) (CPA-PVP-IBMB) containing carboxyl from 4-cyanopentanoic acid (CPA) and peroxide from 1-isopropyl-3(4)-[1-(tert-butyl peroxy)-1-methylethyl]benzene (IBMB) chain transfer agent was synthesized as a surface-active macroinitiator for tailored functionalization of γ-Fe2O3. CPA-PVP-IBMB initiated polymerization of 2-hydroxyethyl methacrylate (HEMA) yielding CPA-PVP-block-poly(2-hydroxyethyl methacrylate) (CPA-PVP-block-PHEMA). γ-Fe2O3 obtained by precipitation was modified by CPA-PVP-IBMB and CPA-PVP-block-PHEMA by “grafting-to using carboxyl groups. “Grafting-from consisted in polymerization of HEMA initiated from surface of CPA-PVP-IBMB-coated γ-Fe2O3 yielding CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles. Tests with mice leukemia L1210 cells confirmed nontoxicity of CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA. CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles were engulfed by murine macrophages J774.2 and magnetically separated from other cells.
  • Poly(N-vinylpyrrolidone) (CPA-PVP-IBMB) containing carboxyl from 4-cyanopentanoic acid (CPA) and peroxide from 1-isopropyl-3(4)-[1-(tert-butyl peroxy)-1-methylethyl]benzene (IBMB) chain transfer agent was synthesized as a surface-active macroinitiator for tailored functionalization of γ-Fe2O3. CPA-PVP-IBMB initiated polymerization of 2-hydroxyethyl methacrylate (HEMA) yielding CPA-PVP-block-poly(2-hydroxyethyl methacrylate) (CPA-PVP-block-PHEMA). γ-Fe2O3 obtained by precipitation was modified by CPA-PVP-IBMB and CPA-PVP-block-PHEMA by “grafting-to using carboxyl groups. “Grafting-from consisted in polymerization of HEMA initiated from surface of CPA-PVP-IBMB-coated γ-Fe2O3 yielding CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles. Tests with mice leukemia L1210 cells confirmed nontoxicity of CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA. CPA-PVP-IBMB-coated γ-Fe2O3/PHEMA nanoparticles were engulfed by murine macrophages J774.2 and magnetically separated from other cells. (en)
Title
  • Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells
  • Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells (en)
skos:prefLabel
  • Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells
  • Surface-initiated polymerization of 2-hydroxyethyl methacrylate from heterotelechelic oligoperoxide-coated .gamma.-Fe2O3 nanoparticles and their engulfment by mammalian cells (en)
skos:notation
  • RIV/61389013:_____/11:00359776!RIV12-AV0-61389013
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA203/09/1242), P(GAP503/10/0664), P(KAN401220801), Z(AV0Z40500505)
http://linked.open...iv/cisloPeriodika
  • 10
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 233511
http://linked.open...ai/riv/idVysledku
  • RIV/61389013:_____/11:00359776
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • 2-hydroxyethyl methacrylate; oligoperoxide; surface-initiated polymerization (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [89F4C4064D03]
http://linked.open...i/riv/nazevZdroje
  • Chemistry of Materials
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 23
http://linked.open...iv/tvurceVysledku
  • Holler, Petr
  • Horák, Daniel
  • Kovářová, Jana
  • Trchová, Miroslava
  • Beneš, Milan J.
  • Babič, Michal
  • Boiko, N.
  • Hevus, O.
  • Klyuchivska, O.
  • Mitina, N.
  • Shagotova, Tetiana
  • Stoika, R.
  • Zaichenko, A.
http://linked.open...ain/vavai/riv/wos
  • 000290594700020
http://linked.open...n/vavai/riv/zamer
issn
  • 0897-4756
number of pages
http://bibframe.org/vocab/doi
  • 10.1021/cm2004215
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