About: Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements     Goto   Sponge   NotDistinct   Permalink

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  • Ultra-high molecular weight polyethylene (UHMWPE) wear particles play a significant role in failures of total joint replacements (TJRs). In this work, we investigated the distribution of these wear particles in periprosthetic tissues obtained from nine revisions of hip TJR. All periprosthetic tissues were combined and mechanically separated into granuloma tissue (containing hard granules visible to the naked eye) and surrounding tissue (without visible granules). Of the total amount of polyethylene particles in the whole granuloma tissue, 72% of particles in the size range 0.1–10 um and 68% of those larger than 10 um were found in granules. Therefore, the formation of granules significantly lowers the effective amount of wear particles available for interaction with reactive cells and seems to be a natural defense mechanism.
  • Ultra-high molecular weight polyethylene (UHMWPE) wear particles play a significant role in failures of total joint replacements (TJRs). In this work, we investigated the distribution of these wear particles in periprosthetic tissues obtained from nine revisions of hip TJR. All periprosthetic tissues were combined and mechanically separated into granuloma tissue (containing hard granules visible to the naked eye) and surrounding tissue (without visible granules). Of the total amount of polyethylene particles in the whole granuloma tissue, 72% of particles in the size range 0.1–10 um and 68% of those larger than 10 um were found in granules. Therefore, the formation of granules significantly lowers the effective amount of wear particles available for interaction with reactive cells and seems to be a natural defense mechanism. (en)
Title
  • Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements
  • Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements (en)
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  • Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements
  • Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements (en)
skos:notation
  • RIV/61389013:_____/10:00347024!RIV11-MSM-61389013
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(2B06096), Z(AV0Z40500505)
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 254748
http://linked.open...ai/riv/idVysledku
  • RIV/61389013:_____/10:00347024
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • joint replacement; polyethylene; wear particles distribution (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [0EDC022D64BC]
http://linked.open...i/riv/nazevZdroje
  • Acta Biomaterialia
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http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Šlouf, Miroslav
  • Pokorný, D.
  • Pavlova, Ewa
  • Zolotarevova, E.
  • Sosna, A.
  • Gallo, J.
  • Entlicher, G.
  • Veselý, F.
http://linked.open...ain/vavai/riv/wos
  • 000281318400026
http://linked.open...n/vavai/riv/zamer
issn
  • 1742-7061
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