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Description
  • The intrinsic and external factors governing the stability of unnatural motifs in nucleic acids are discussed. The former are described by means of high-level ab initio calculations on the investigated base pairs, while the latter are derived from an analysis of the molecular dynamics trajectories. Their combined description is proposed, and short DNA duplex containing the 3-fluorobenzene self-pair is treated as the test case for the new approach.
  • The intrinsic and external factors governing the stability of unnatural motifs in nucleic acids are discussed. The former are described by means of high-level ab initio calculations on the investigated base pairs, while the latter are derived from an analysis of the molecular dynamics trajectories. Their combined description is proposed, and short DNA duplex containing the 3-fluorobenzene self-pair is treated as the test case for the new approach. (en)
Title
  • The combined treatment of the intrinsic and external contributions to the stability of the nucleic acids containing unnatural nucleosides
  • The combined treatment of the intrinsic and external contributions to the stability of the nucleic acids containing unnatural nucleosides (en)
skos:prefLabel
  • The combined treatment of the intrinsic and external contributions to the stability of the nucleic acids containing unnatural nucleosides
  • The combined treatment of the intrinsic and external contributions to the stability of the nucleic acids containing unnatural nucleosides (en)
skos:notation
  • RIV/61389013:_____/08:00314317!RIV10-AV0-61389013
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  • P(KJB400500602), Z(AV0Z40500505)
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  • 360417
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  • RIV/61389013:_____/08:00314317
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  • nucleic acid; nucleobase; hydrogen-bonding; stacking (en)
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http://linked.open...ontrolniKodProRIV
  • [C92E096F9686]
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  • Bucharest
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  • Bucharest
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  • MACMESE 2008: PROCEEDINGS OF THE 10TH WSEAS INTERNATIONAL CONFERENCE ON MATHEMATICAL AND COMPUTATIONAL METHODS IN SCIENCE AND ENGINEERING
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  • Czernek, Jiří
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  • 000262436800052
http://linked.open.../riv/zahajeniAkce
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number of pages
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  • World Scientific and Engineerin Academy and Society Press
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  • 978-960-474-019-2
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