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  • Oligopeptid YESIGVAVS odvozený od lamininu byl kovalentně navázán na kopolymery na bázi N-(2-hydroxypropyl)methakrylamidu (HPMA) Dva peptidy odvozené od gonadotropin uvolňujícího hormonu (GnRH) byly také navázány na HPMA kopolymery a použity pro modifikaci adenovirových vektorů pro dopravu genů. Byl studován vliv polymerního obalu se směrujícími peptidy i bez nich na expresi modelového genu. (cs)
  • A laminin derived targeting oligopeptide sequence YESIGVAVS was covalently linked to N-(2-hydroxypropyl)methacrylamide (HPMA) based copolymers. Two peptides derived from gonadotropin releasing hormone (GnRH) were also conjugated to HPMA copolymers and used for modification of adenoviral gene delivery vectors. The influence of the polymer coating with and without the targeting peptide on the expression of reporter genes was investigated.
  • A laminin derived targeting oligopeptide sequence YESIGVAVS was covalently linked to N-(2-hydroxypropyl)methacrylamide (HPMA) based copolymers. Two peptides derived from gonadotropin releasing hormone (GnRH) were also conjugated to HPMA copolymers and used for modification of adenoviral gene delivery vectors. The influence of the polymer coating with and without the targeting peptide on the expression of reporter genes was investigated. (en)
Title
  • Oligopeptides as targeting structures in cancer therapy
  • Oligopeptides as targeting structures in cancer therapy (en)
  • Oligopeptidy jako směrující struktury v nádorové terapii (cs)
skos:prefLabel
  • Oligopeptides as targeting structures in cancer therapy
  • Oligopeptides as targeting structures in cancer therapy (en)
  • Oligopeptidy jako směrující struktury v nádorové terapii (cs)
skos:notation
  • RIV/61389013:_____/05:00323162!RIV09-AV0-61389013
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z40500505)
http://linked.open...iv/cisloPeriodika
  • 1-3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 534260
http://linked.open...ai/riv/idVysledku
  • RIV/61389013:_____/05:00323162
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • oligopeptide targeting; HPMA; prostate cancer (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [565F8DBFD495]
http://linked.open...i/riv/nazevZdroje
  • Journal of Controlled Release
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 101
http://linked.open...iv/tvurceVysledku
  • Etrych, Tomáš
  • Pechar, Michal
  • Ulbrich, Karel
  • Stevenson, M.
  • Seymour, L.
  • Fabra, A.
http://linked.open...ain/vavai/riv/wos
  • 000226086800062
http://linked.open...n/vavai/riv/zamer
issn
  • 0168-3659
number of pages
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