About: Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers     Goto   Sponge   NotDistinct   Permalink

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Description
  • Various amounts of one of three different types of cleavable methoxy polyethylene glycol (mPEG)-phospholipids or of a non-cleavable counterpart (mPEG-DSPE) were included into pH-sensitive liposome formulations containing dioleoylphosphatidylethanolamine and cholesterylhemisuccinate at a 6:4 molar ratio, and the effect on plasma clearance and contents release rates was determined.
  • Various amounts of one of three different types of cleavable methoxy polyethylene glycol (mPEG)-phospholipids or of a non-cleavable counterpart (mPEG-DSPE) were included into pH-sensitive liposome formulations containing dioleoylphosphatidylethanolamine and cholesterylhemisuccinate at a 6:4 molar ratio, and the effect on plasma clearance and contents release rates was determined. (en)
  • Různá množství jednoho ze tří typů štěpitelných methoxypolyethylenglykolů (mPEG)-fosfolipidu nebo jeho neštěpitelného analoga (mPEG-DSPE) byla zabudována do pH-sensitivních liposomů s dioleoylfosfatidylethanolaminem a cholesterylhemisukcinátem v poměru 6:4 Byl studován vliv množství mPEG-fosfolipidu na eliminaci liposomu z krevní plasmy a na rychlost uvolňováni jejich obsahů. (cs)
Title
  • Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers
  • Farmakologické vlastnosti liposomů na bázi dioleoylfosfatidylethanolamine/cholesterylhemisukcinátů s různými typy štěpitelných lipopolymerů (cs)
  • Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers (en)
skos:prefLabel
  • Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers
  • Farmakologické vlastnosti liposomů na bázi dioleoylfosfatidylethanolamine/cholesterylhemisukcinátů s různými typy štěpitelných lipopolymerů (cs)
  • Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers (en)
skos:notation
  • RIV/61389013:_____/04:00105813!RIV/2005/AV0/A55005/N
http://linked.open.../vavai/riv/strany
  • 185;198
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(KSK4050111), Z(AV0Z4050913)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 579303
http://linked.open...ai/riv/idVysledku
  • RIV/61389013:_____/04:00105813
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • pH-sensitive liposomes;polyethyleneglycol;pharmacokinetics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [5F6C64517DFA]
http://linked.open...i/riv/nazevZdroje
  • Pharmacological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 49
http://linked.open...iv/tvurceVysledku
  • Pechar, Michal
  • Zhang, J. X.
  • Allen, T. M.
  • Mullah, N.
  • Zalipsky, S.
http://linked.open...n/vavai/riv/zamer
issn
  • 1043-6618
number of pages
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