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  • This study was aimed to analyze the effects of the antiarrhythmic drug ajmaline (a known inhibitor of the fast sodium current INa) on the potassium currents, namely the transient outward current (Ito) and the current measured at the end of a depolarizing pulse (IK) in rat ventricular myocytes. Both currents were inhibited in concentration- and voltage-dependent manner. However, the effects were frequency-independent.
  • This study was aimed to analyze the effects of the antiarrhythmic drug ajmaline (a known inhibitor of the fast sodium current INa) on the potassium currents, namely the transient outward current (Ito) and the current measured at the end of a depolarizing pulse (IK) in rat ventricular myocytes. Both currents were inhibited in concentration- and voltage-dependent manner. However, the effects were frequency-independent. (en)
Title
  • Voltage clamp analysis of ajmaline-induced block of potassium currents in ventricular myocytes.
  • Voltage clamp analysis of ajmaline-induced block of potassium currents in ventricular myocytes. (en)
skos:prefLabel
  • Voltage clamp analysis of ajmaline-induced block of potassium currents in ventricular myocytes.
  • Voltage clamp analysis of ajmaline-induced block of potassium currents in ventricular myocytes. (en)
skos:notation
  • RIV/61388998:_____/02:51020139!RIV/2003/AV0/A51003/N
http://linked.open.../vavai/riv/strany
  • 217;219
http://linked.open...avai/riv/aktivita
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  • Z(AV0Z2076919)
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  • 669374
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  • RIV/61388998:_____/02:51020139
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  • cardiac cell; potassium currents; ajmaline (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [5DC0F42F2DFD]
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  • Brno [CZ]
http://linked.open...i/riv/mistoVydani
  • Brno
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  • Analysis of biomedical signals and images.
http://linked.open...in/vavai/riv/obor
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  • Pásek, Michal
  • Šimurda, J.
  • Šimurdová, M.
  • Bahníková, M.
  • Matějovič, P.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Vysoké učení technické v Brně
https://schema.org/isbn
  • 80-214-2120-7
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