About: Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Heterocytous cyanobacteria from various habitats were screened for toxicity to brine shrimp Artemia salina and the murine lymphoblastic cell line Sp/2 in order to compare these two testing models for evaluation of risk posed by cyanobacteria to human health. Methanol extracts of biomass and cultivation media were tested for toxicity and selected extracts were fractionated to determine the active fraction. We found a significant toxic effect to A. sauna and to Sp/2 cells in 5.2% and 31% of studied extracts, respectively. Only 8.6% of the tested strains were highly toxic to both A. sauna and the Sp/2 cell line, and only two of the tested strains were toxic to A. sauna and not to the murine cell line Heterocytous cyanobacteria from various habitats were screened for toxicity to brine shrimp Artemia salina and the murine lymphoblastic cell line Sp/2 in order to compare these two testing models for evaluation of risk posed by cyanobacteria to human health. Methanol extracts of biomass and cultivation media were tested for toxicity and selected extracts were fractionated to determine the active fraction. We found a significant toxic effect to A. sauna and to Sp/2 cells in 5.2% and 31% of studied extracts, respectively. Only 8.6% of the tested strains were highly toxic to both A. sauna and the Sp/2 cell line, and only two of the tested strains were toxic to A. sauna and not to the murine cell line (en)
Title	Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina (en)
skos:prefLabel	Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina (en)
skos:notation	RIV/61388971:_____/11:00372518!RIV12-AV0-61388971
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP504/10/1501), Z(AV0Z50200510), Z(AV0Z60170517), Z(AV0Z60660521), Z(MSM6007665801), Z(MSM6007665808)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hrouzek, Pavel Kopecký, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	192562
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00372518
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Secondary metabolites; Brine shrimp bioassay; Health risk assessment (en)
http://linked.open.../riv/klicoveSlovo	Brine shrimp bioassay Health risk assessment Secondary metabolites
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B928446423F7]
http://linked.open...i/riv/nazevZdroje	Toxicon
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Taxonomic revision of the genera Anabaena and Aphanizomenon (cyanobacteria) based on complex phenotypic and molecular approach
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Hisem, D. Hrouzek, Pavel Kopecký, Jiří Lukešová, Alena Skácelová, K. Tomek, P. Tomšíčková, J. Zapomělová, Eliška
http://linked.open...ain/vavai/riv/wos	000286997300009
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Struktura, funkce a vývoj vodních ekosystémů Relationships between the structure and function of decomposer food web in soil EKOLOGICKÉ, EVOLUČNÍ A EXPERIMENTÁLNĚ BIOLOGICKÉ PŘÍSTUPY KE STUDIU VZNIKU A VÝZNAMU BIODIVERZITY Fyzikální biologie -nové přístupy v biologickém výzkumu
issn	0041-0101
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.toxicon.2010.10.002

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