About: Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor

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About: Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The occurrence of phosphorylated proteins in ribosomes of Streptomyces coelicolor was investigated. Little is known about which biological functions these posttranslational modifications might fulfil. A protein kinase associated with ribosomes phosphorylated six ribosomal proteins of the small subunit (S3, S4, S12, S13, S14 and S18) and seven ribosomal proteins of the large subunit (L2, L3, L7/L12, L16, L17, L23 and L27). The ribosomal proteins were phosphorylated mainly on the Ser/Thr residues. Phosphorylation of the ribosomal proteins influences ribosomal subunits association. Ribosomes with phosphorylated proteins were used to examine poly (U) translation activity. Phosphorylation induced about 50 percent decrease in polyphenylalanine synthesis The occurrence of phosphorylated proteins in ribosomes of Streptomyces coelicolor was investigated. Little is known about which biological functions these posttranslational modifications might fulfil. A protein kinase associated with ribosomes phosphorylated six ribosomal proteins of the small subunit (S3, S4, S12, S13, S14 and S18) and seven ribosomal proteins of the large subunit (L2, L3, L7/L12, L16, L17, L23 and L27). The ribosomal proteins were phosphorylated mainly on the Ser/Thr residues. Phosphorylation of the ribosomal proteins influences ribosomal subunits association. Ribosomes with phosphorylated proteins were used to examine poly (U) translation activity. Phosphorylation induced about 50 percent decrease in polyphenylalanine synthesis (en)
Title	Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor (en)
skos:prefLabel	Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor Phosphorylation of ribosomal proteins influences subunit association and translation of poly (U) in Streptomyces coelicolor (en)
skos:notation	RIV/61388971:_____/11:00371869!RIV12-AV0-61388971
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GA303/09/0475), P(GA310/07/1009), P(GAP302/10/0468), P(IAA500110805), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Mikulík, Karel Bobek, Jan Smětáková, Magdalena Bezoušková, Silvia Ziková, Alice
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	220218
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00371869
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ESCHERICHIA-COLI RIBOSOME; ELONGATION-FACTOR-G; MESSENGER-RNA (en)
http://linked.open.../riv/klicoveSlovo	MESSENGER-RNA ELONGATION-FACTOR-G ESCHERICHIA-COLI RIBOSOME
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[6B07FCD0313C]
http://linked.open...i/riv/nazevZdroje	Molecular BioSystems
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of mechanisms of adipokine autocrine effects on glucose and lipid metabolism Biocomputational prediction of intergenic structures in Actinomyces Regulatory role of small-noncoding RNAs in gene expression Analysis and modelling of gene expression in search for regulatory RNAs affecting antibiotic production in Streptomyces
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Bezoušková, Silvia Bobek, Jan Mikulík, Karel Smětáková, Magdalena Ziková, Alice
http://linked.open...ain/vavai/riv/wos	000287367100026
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	1742-206X
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1039/c0mb00174k

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