About: Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms

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About: Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ferritin is a storage protein that plays a key role in iron metabolism. In this study, we report on the sequence characterization of a ferritin-coding cDNA in Eisenia andrei earthworms isolated by RT-PCR using degenerated primers, and we suggest the presence of a putative IRE in the 5-UTR of ferritin mRNA. The obtained ferritin sequence was compared with those of other animals showing sequence and structure homology in consensus sites, including the iron-responsive element (IRE) and ferroxidase centers. Despite the sequence homology in the E. andrei mRNA of ferritin with the sequences of other animals in consensus IRE sites, the presented cytosine in the IRE of E. andrei ferritin in the expected position does not form a conventional bulge Ferritin is a storage protein that plays a key role in iron metabolism. In this study, we report on the sequence characterization of a ferritin-coding cDNA in Eisenia andrei earthworms isolated by RT-PCR using degenerated primers, and we suggest the presence of a putative IRE in the 5-UTR of ferritin mRNA. The obtained ferritin sequence was compared with those of other animals showing sequence and structure homology in consensus sites, including the iron-responsive element (IRE) and ferroxidase centers. Despite the sequence homology in the E. andrei mRNA of ferritin with the sequences of other animals in consensus IRE sites, the presented cytosine in the IRE of E. andrei ferritin in the expected position does not form a conventional bulge (en)
Title	Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms (en)
skos:prefLabel	Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms (en)
skos:notation	RIV/61388971:_____/11:00366799!RIV12-AV0-61388971
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(2B06155), P(GA206/07/0378), P(GD310/08/H077), P(IAA600200704), P(LC07017), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Halada, Petr Dvořák, Jiří Šilerová, Marcela Bilej, Martin Procházková, Petra Škanta, František Roubalová, Radka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	213483
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00366799
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Earthworms; Invertebrates; Ferritin (en)
http://linked.open.../riv/klicoveSlovo	Earthworms Ferritin Invertebrates
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[A1B6F7B84672]
http://linked.open...i/riv/nazevZdroje	Gene
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Evolution of mucosal antimicrobial immunity The importance of soil microflora for defense mechanisms of earthworms Identification of new markers for molecular diagnosis of inflammatory and tumor diseases. Regulation of immunological mechanisms in health and disease:Development of new diagnostic and therapeutic approaches Oncoproteomics Centre
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	485
http://linked.open...iv/tvurceVysledku	Dvořák, Jiří Halada, Petr Šilerová, Marcela Bilej, Martin Procházková, Petra Roubalová, Radka Škanta, František
http://linked.open...ain/vavai/riv/wos	000295069800003
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	0378-1119
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.gene.2011.06.010

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