About: Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Gliadins, and primarily a-gliadins containing several sequences such as aa 31-49, aa 56-88 (33-mer), aa 57-68, and aa 69-82, are critical in the induction of immune response or toxic reaction leading to the development of celiac disease (CLD). The role of IgA anti-gliadin antibodies (IgA AGA) is unknown. To this end, we prepared several humanized monoclonal IgA AGA using transgenic α1KI mice. Employing Pepscan with overlapping decapeptides of a-gliadin we observed a robust similarity between the specificity of humanized mouse monoclonal IgA AGA and IgA AGA from patients with florid CLD Gliadins, and primarily a-gliadins containing several sequences such as aa 31-49, aa 56-88 (33-mer), aa 57-68, and aa 69-82, are critical in the induction of immune response or toxic reaction leading to the development of celiac disease (CLD). The role of IgA anti-gliadin antibodies (IgA AGA) is unknown. To this end, we prepared several humanized monoclonal IgA AGA using transgenic α1KI mice. Employing Pepscan with overlapping decapeptides of a-gliadin we observed a robust similarity between the specificity of humanized mouse monoclonal IgA AGA and IgA AGA from patients with florid CLD (en)
Title	Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice (en)
skos:prefLabel	Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice Similarity of fine specificity of IgA-gliadin antibodies between patients with celiac disease and humanized α 1KI mice (en)
skos:notation	RIV/61388971:_____/11:00361616!RIV12-AV0-61388971
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA310/07/0414), P(IAA500200709), P(NS9705), S, Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Tučková, Ludmila Tlaskalová-Hogenová, Helena Pekáriková, Aneta Sánchez, Daniel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	229272
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00361616
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	alpha 1KI mouse; IgA antibodies; celiac disease (en)
http://linked.open.../riv/klicoveSlovo	celiac disease IgA antibodies alpha 1KI mouse
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1DA6A3926960]
http://linked.open...i/riv/nazevZdroje	Journal of Agricultural and Food Chemistry
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Occurrence, analysis of fine specificity and biological role of serum autoantibodies against calreticulin and tissue transglutaminase in patients with oncological diseases and selected risk groups The association of chronic liver disease with coeliac disease The role of innate and adaptive immunity in development of gluten-sensitive entheropathy
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	59
http://linked.open...iv/tvurceVysledku	Hoffmanová, I. Tučková, Ludmila Drastich, P. Tlaskalová, Helena Sánchez, Daniel Champier, G. Cogné, M. Cuvillier, A. Mothes, T. Pekáriková, Aneta
http://linked.open...ain/vavai/riv/wos	000289050400047
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	0021-8561
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1021/jf1044519

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software