About: Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Natural polyphenols are known to be oxidized by free radicals, which partially explains the antioxidant properties of a number of these compounds. This oxidation may also be used to synthesise new compounds of biological interest, for example, dimers. The present theoretical study describes the existing experimental evidence showing that silybin and dehydrosilybin [natural polyphenols isolated from milk thistle (Silybum marianum)] form dimers regioselectively Natural polyphenols are known to be oxidized by free radicals, which partially explains the antioxidant properties of a number of these compounds. This oxidation may also be used to synthesise new compounds of biological interest, for example, dimers. The present theoretical study describes the existing experimental evidence showing that silybin and dehydrosilybin [natural polyphenols isolated from milk thistle (Silybum marianum)] form dimers regioselectively (en)
Title	Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory (en)
skos:prefLabel	Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory (en)
skos:notation	RIV/61388971:_____/11:00360717!RIV12-AV0-61388971
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP207/10/0288), P(LD11051), P(OC08049), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Gažák, Radek Křen, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	194721
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00360717
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antioxidants; computational chemistry; dimerization (en)
http://linked.open.../riv/klicoveSlovo	antioxidants computational chemistry dimerization
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[3525AEE3B253]
http://linked.open...i/riv/nazevZdroje	ChemPhysChem
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Isosilybin: Combined chemo-enzymatic approaches for preparation of optically pure stereoisomers and derivatives. Synthesis and biological evaluation of sulfated silybin metabolites. Inhibitors of Angiogenesis: Design, Synthesis and Biological Exploitation
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	12
http://linked.open...iv/tvurceVysledku	Gažák, Radek Křen, Vladimír Assfeld, X. Duroux, J.-L. Košinová, P. Lazzaroni, R. Trouillas, P.
http://linked.open...ain/vavai/riv/wos	000289264400014
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	1439-4235
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/cphc.201100066

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