About: Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense

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About: Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In contrast to liquid cultures of Saccharomyces cerevisiae, where population fitness depends on its ROS scavenging capability, the yeast cells growing in colonies capable of ammonia signaling use a broader protective strategy. Cells in colonies activate an alternative metabolism that prevents ROS production. Colonies of the strain deficient in cytosolic superoxide dismutase Sod1p producing ammonia thus developed the same way as wt colonies. Colonies of strains deficient in Sod2p or cytosolic catalase Ctt1p failing in ammonia production and sufficient activation of the alternative metabolism have prominent developmental problems. The data indicate that colony disorders are not accompanied by ROS burst but could be a consequence of metabolic defects In contrast to liquid cultures of Saccharomyces cerevisiae, where population fitness depends on its ROS scavenging capability, the yeast cells growing in colonies capable of ammonia signaling use a broader protective strategy. Cells in colonies activate an alternative metabolism that prevents ROS production. Colonies of the strain deficient in cytosolic superoxide dismutase Sod1p producing ammonia thus developed the same way as wt colonies. Colonies of strains deficient in Sod2p or cytosolic catalase Ctt1p failing in ammonia production and sufficient activation of the alternative metabolism have prominent developmental problems. The data indicate that colony disorders are not accompanied by ROS burst but could be a consequence of metabolic defects (en)
Title	Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense (en)
skos:prefLabel	Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense Yeast Colony Survival Depends on Metabolic Adaptation and Cell Differentiation Rather Than on Stress Defense (en)
skos:notation	RIV/61388971:_____/09:00334430!RIV10-MSM-61388971
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/08/0718), P(GA525/05/0297), P(LC531), Z(AV0Z50200510), Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika	47
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Váchová, Libuše
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	352179
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/09:00334430
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	LONG-TERM SURVIVAL; SACCHAROMYCES-CEREVISIAE; SUPEROXIDE-DISMUTASE (en)
http://linked.open.../riv/klicoveSlovo	LONG-TERM SURVIVAL SACCHAROMYCES-CEREVISIAE SUPEROXIDE-DISMUTASE
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[72774220F6EB]
http://linked.open...i/riv/nazevZdroje	Journal of Biological Chemistry
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre on molecular biology and physiology of yeast communities Molecular mechanisms involved in long-term survival of yeasts under laboratory and %22natural%22 conditions Role of ammonia signalling in yeast colony differentiation, development, ageing and survival: Molecular mechanisms and functions.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	284
http://linked.open...iv/tvurceVysledku	Palková, Z. Váchová, Libuše Čáp, M.
http://linked.open...ain/vavai/riv/wos	000272028400039
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Signaling and cellular response mechanisms
issn	0021-9258
number of pages	10 (xsd:int)

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