About: Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells     Goto   Sponge   NotDistinct   Permalink

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  • The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these proteins markedly decreased in relation with the apoptosis progression and all isoforms underwent truncation, which probably corresponds to the removal of several C-terminal amino acids. The observed 14-3-3 modifications were partially blocked by caspase-3 inhibition
  • The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these proteins markedly decreased in relation with the apoptosis progression and all isoforms underwent truncation, which probably corresponds to the removal of several C-terminal amino acids. The observed 14-3-3 modifications were partially blocked by caspase-3 inhibition (en)
Title
  • Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells
  • Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells (en)
skos:prefLabel
  • Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells
  • Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells (en)
skos:notation
  • RIV/61388971:_____/09:00328368!RIV10-MZ0-61388971
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR9243), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 320495
http://linked.open...ai/riv/idVysledku
  • RIV/61388971:_____/09:00328368
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • k562; apoptosis; 14-3-3 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [99F1707088F3]
http://linked.open...i/riv/nazevZdroje
  • Journal of Cellular Biochemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 106
http://linked.open...iv/tvurceVysledku
  • Halada, Petr
  • Kavan, Daniel
  • Hrkal, Z.
  • Grebeňová, D.
  • Kuželová, K.
  • Pluskalová, M.
http://linked.open...ain/vavai/riv/wos
  • 00026445630002
http://linked.open...n/vavai/riv/zamer
issn
  • 0730-2312
number of pages
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