| Attributes | Values |
|---|
| rdf:type
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| Description
| - The synthetic access of either b-D-ManNAc-(14)-D-Glc (5) is b-D-TalNAc-(14)-D-Glc (6) disaccharides has been effectively improved with respect to previous syntheses (J. Carbohydr. Chem. 2000, 19, 79–91 and 2004, 23, 179–190), optimizing the preparation of suitably protected 4-O-(2-acetamido-2-deoxy-3,4-O-isopropylidene-b-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal derivatives obtained by complete stereoselective LiAlH4 reduction of new 20-oximino precursors derived from lactose. The affinity of the disaccharides 5 and 6 toward the natural killer cell NKR-P1 and CD69 receptors has been evaluated and discussed
- The synthetic access of either b-D-ManNAc-(14)-D-Glc (5) is b-D-TalNAc-(14)-D-Glc (6) disaccharides has been effectively improved with respect to previous syntheses (J. Carbohydr. Chem. 2000, 19, 79–91 and 2004, 23, 179–190), optimizing the preparation of suitably protected 4-O-(2-acetamido-2-deoxy-3,4-O-isopropylidene-b-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal derivatives obtained by complete stereoselective LiAlH4 reduction of new 20-oximino precursors derived from lactose. The affinity of the disaccharides 5 and 6 toward the natural killer cell NKR-P1 and CD69 receptors has been evaluated and discussed (en)
- Byla vylepšena syntetická dostupnost disacharidů b-D-ManNAc-(1-4)-D-Glc (5) a b-D-TalNAc-(1-4)-D-Glc (6) oproti dřívějším syntetickým postupům (J. Carbohydr. Chem. 2000, 19, 79–91 and 2004, 23, 179–190). Došlo ke zlepšení přípravy vhodně chráněných acetálových derivátů 4-O-(2-acetamido-2-deoxy-3,4-O-isopropylidene-b-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucosy získaných kompletní stereoselektivní redukcí nového 2-oximino prekurzoru připraveného z laktózy. Byla zkoumána a diskutována afinita disacharidů 5 a 6 k aktivačním receptorům NK buněk NKR-P1 a CD69 (cs)
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| Title
| - Improved Preparation of Beta-D-ManNAc-(1-4)-D-Glc and Beta-d-TalNAc-(1-4)-D-Glc Disaccharides and Evaluation of Their Activating Properties on the Natural Killer Cells NKR-P1 and CD69 Receptors
- Vylepšená příprava Beta-D-ManNAc-(1-4)-D-Glc a Beta-d-TalNAc-(1-4)-D-Glc disacharidů a stanovení jejich aktivačních vlastností vůči aktivačním receptorům NK buněk NKR-P1 a CD69 (cs)
- Improved Preparation of Beta-D-ManNAc-(1-4)-D-Glc and Beta-d-TalNAc-(1-4)-D-Glc Disaccharides and Evaluation of Their Activating Properties on the Natural Killer Cells NKR-P1 and CD69 Receptors (en)
|
| skos:prefLabel
| - Improved Preparation of Beta-D-ManNAc-(1-4)-D-Glc and Beta-d-TalNAc-(1-4)-D-Glc Disaccharides and Evaluation of Their Activating Properties on the Natural Killer Cells NKR-P1 and CD69 Receptors
- Vylepšená příprava Beta-D-ManNAc-(1-4)-D-Glc a Beta-d-TalNAc-(1-4)-D-Glc disacharidů a stanovení jejich aktivačních vlastností vůči aktivačním receptorům NK buněk NKR-P1 a CD69 (cs)
- Improved Preparation of Beta-D-ManNAc-(1-4)-D-Glc and Beta-d-TalNAc-(1-4)-D-Glc Disaccharides and Evaluation of Their Activating Properties on the Natural Killer Cells NKR-P1 and CD69 Receptors (en)
|
| skos:notation
| - RIV/61388971:_____/08:00311284!RIV09-AV0-61388971
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(1M0505), P(IAA400200503), P(LC06010), P(OC 136), Z(AV0Z50200510), Z(MSM0021620808)
|
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/61388971:_____/08:00311284
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - reductions; nkr-p1 receptor; nk cells (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Journal of Carbohydrate Chemistry
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Bezouška, Karel
- Křen, Vladimír
- Křenek, Karel
- Catelani, G.
- Attolino, E.
- Bonaccorsi, F.
- D'Andrea, F.
|
| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
| |
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