About: Arachidonic Acid Derivatives in the Exhaled Breath Condensate in Pneumoconioses and their Correlation with Individual Factors

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Tato studie potvrzuje, že analýza leukotrienů (LT) v kondenzátu vydechovaného vzduchu je užitečná u subjektů exponovaných fibrogennímu prachu, především LTD4 a LT E4. LT D4 byly vyšší u subjektů s vyšší expozicí azbestu a silikotiků a mohou ukazovat na aktivitu fibrogenních procesů; LT E4 koreloval s hladinou expozice, %22asbestoroky%22 a kategorií expozice křemíku. LT C4 koreloval s chronickým obstrukčním pulmonarním onemocněním. Žádná korelace nebyla pozorována mezi konzumací alkoholu, cigaretami/den nebo systemickým onemocněním a LTD4 a LTE4, což podporuje teorii, že analýza vydechovaného kondenzátu vzduchu odráží výhradně pochody odehrávající se v plicích. (cs) This study confirms that exhaled breath condensate analysis of leukotriens (LTs) is useful in fibrogenic dust exposed subjects, especially LTD4 and LTE4. LT D4 was higher both in the subjects with asbestos exposure and in the silicotics and might point to the activity of the fibrogenic process; on the other hand LT E4 correlated with the level of exposure - asbestos fiber-years and category of silica exposure. On the other hand, LT C4 correlated with chronic obstructive pulmonary disease. No correlation with daily alcohol consumption, cigarettes/day or systemic diseases was found for LTD4 and LTE4, which supports the theory that analysis of exhaled breath condensate reflects solely processes ongoing in the lungs. This study confirms that exhaled breath condensate analysis of leukotriens (LTs) is useful in fibrogenic dust exposed subjects, especially LTD4 and LTE4. LT D4 was higher both in the subjects with asbestos exposure and in the silicotics and might point to the activity of the fibrogenic process; on the other hand LT E4 correlated with the level of exposure - asbestos fiber-years and category of silica exposure. On the other hand, LT C4 correlated with chronic obstructive pulmonary disease. No correlation with daily alcohol consumption, cigarettes/day or systemic diseases was found for LTD4 and LTE4, which supports the theory that analysis of exhaled breath condensate reflects solely processes ongoing in the lungs. (en)
Title	Arachidonic Acid Derivatives in the Exhaled Breath Condensate in Pneumoconioses and their Correlation with Individual Factors Deriváty kyseliny arachidonové v kondenzátu vydechovaného vzduchu u Pneumokonióz a korelace s jednotlivými faktory (cs) Arachidonic Acid Derivatives in the Exhaled Breath Condensate in Pneumoconioses and their Correlation with Individual Factors (en)
skos:prefLabel	Arachidonic Acid Derivatives in the Exhaled Breath Condensate in Pneumoconioses and their Correlation with Individual Factors Deriváty kyseliny arachidonové v kondenzátu vydechovaného vzduchu u Pneumokonióz a korelace s jednotlivými faktory (cs) Arachidonic Acid Derivatives in the Exhaled Breath Condensate in Pneumoconioses and their Correlation with Individual Factors (en)
skos:notation	RIV/61388971:_____/07:00319397!RIV09-MZ0-61388971
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9338), Z(AV0Z40400503), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	s
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Kuzma, Marek
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	410634
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/07:00319397
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	silica; asbestos; leukotrienes (en)
http://linked.open.../riv/klicoveSlovo	asbestos leukotrienes silica
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[900EDA6D803D]
http://linked.open...i/riv/nazevZdroje	Chemické listy
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Influence of individual factors on the levels of markers of oxidative stress in biological materials of subjects with exposure to asbestos and silica
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	101
http://linked.open...iv/tvurceVysledku	Kuzma, Marek Navrátil, Tomáš Fenclová, Z. Pelclová, D. Lebedová, J. Klusáčková, P. Kačer, J.
http://linked.open...n/vavai/riv/zamer	Struktura, reaktivita a dynamika molekulárních a biomolekulárních systémů: teorie, experiment, aplikace Microorganisms in Research and Biotechnology
issn	1213-7103
number of pages	3 (xsd:int)

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