About: The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C     Goto   Sponge   NotDistinct   Permalink

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  • We analyzed the steady-state composition of the iron-regulated proteome and transcriptome of an invasive serogroup C clinical isolate of Neisseria meningitidis. The proteome of meningococci grown under iron-depleted and iron-replete conditions was analyzed by 2-DE and proteins exhibiting significantly altered expression were identified by MALDI-TOF MS analysis. In parallel, total RNA was isolated from the same cultures and iron-regulated genes were identified using whole-genome DNA microarrays
  • We analyzed the steady-state composition of the iron-regulated proteome and transcriptome of an invasive serogroup C clinical isolate of Neisseria meningitidis. The proteome of meningococci grown under iron-depleted and iron-replete conditions was analyzed by 2-DE and proteins exhibiting significantly altered expression were identified by MALDI-TOF MS analysis. In parallel, total RNA was isolated from the same cultures and iron-regulated genes were identified using whole-genome DNA microarrays (en)
  • Analyzovali jsme železem regulovaný proteom a transkriptom invazivního klinického izolátu serotypu C Neisserie meningitidis. Proteom meningokoků kultivovaných za podmínek limitace železem a za dostatku železa byl analyzován 2-DE a proteiny, které vykazovaly významně změněnou expresi, byly identifikovány MALDI-TOF MS analýzou. Souběžně byla izolována totální RNA ze stejných kultur a železem regulované geny byly identifikovány pomocí celogenomových DNA chipů (cs)
Title
  • The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C
  • The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C (en)
  • Železem regulovaný transkriptom a proteom Neisseria meningitidis seroskupiny C (cs)
skos:prefLabel
  • The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C
  • The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C (en)
  • Železem regulovaný transkriptom a proteom Neisseria meningitidis seroskupiny C (cs)
skos:notation
  • RIV/61388971:_____/06:00054443!RIV07-GA0-61388971
http://linked.open.../vavai/riv/strany
  • 6194;6206
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1G46068), P(GA310/04/0804), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika
  • 23
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 480452
http://linked.open...ai/riv/idVysledku
  • RIV/61388971:_____/06:00054443
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • iron regulation; Neisseria meningitidis; proteome (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [C68CB6ABAB99]
http://linked.open...i/riv/nazevZdroje
  • Proteomics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Halada, Petr
  • Osička, Radim
  • Weiser, Jaroslav
  • Šebo, Peter
  • Novotná, Jana
  • Bezoušková, Silvia
  • Vohradský, Jiří
  • Basler, Marek
  • Linhartová, Irena
http://linked.open...n/vavai/riv/zamer
issn
  • 1615-9853
number of pages
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