About: Novel antimicrobial peptides

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20130306&DB=EPODOC&locale=en_EP&CC=EP&NR=2396020B1&KC=B1&ND=4
Description	The invention involves two novel peptides of the formulas H-Gly -Met-Trp -Ser-Lys-Ile-Leu-Gly -His-Leu-Ile-Arg -NH2 (I) and H-Gly -Lys-Trp -Met-Ser-Leu-Leu-Lys -His-Ile-Leu-Lys-NH2 (II) isolated from venom reservoirs of primitively eusocial bees Halictus sexcintus and their synthetic analogs possessing biological effects, prepared by the substitution of an amino acid in position 4, 11 or 12 of formula (I) or in position 4 of formula (II) by an amino acid lysine. Described is also their usage for the preparation of medicaments for the treatment of microbial, parasitic and fungal diseases and for the cancer treatment. The invention involves two novel peptides of the formulas H-Gly -Met-Trp -Ser-Lys-Ile-Leu-Gly -His-Leu-Ile-Arg -NH2 (I) and H-Gly -Lys-Trp -Met-Ser-Leu-Leu-Lys -His-Ile-Leu-Lys-NH2 (II) isolated from venom reservoirs of primitively eusocial bees Halictus sexcintus and their synthetic analogs possessing biological effects, prepared by the substitution of an amino acid in position 4, 11 or 12 of formula (I) or in position 4 of formula (II) by an amino acid lysine. Described is also their usage for the preparation of medicaments for the treatment of microbial, parasitic and fungal diseases and for the cancer treatment. (en)
Title	Novel antimicrobial peptides Novel antimicrobial peptides (en)
skos:prefLabel	Novel antimicrobial peptides Novel antimicrobial peptides (en)
skos:notation	RIV/61388963:_____/13:00394191!RIV14-GA0-61388963
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/08/0536), Z(AV0Z40550506)
http://linked.open...cisloPatentuVzoru	EP2396020
http://linked.open...eleniPatentuVzoru	2013-03-06 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Monincová, Lenka Slaninová, Jiřina Fučík, Vladimír Borovičková, Lenka Čeřovský, Václav Cvačka, Josef Hovorka, Oldřich Voburka, Zdeněk
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	92342
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/13:00394191
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antimicrobial peptides; bee venom; hemolytic activity; NMR spectroscopy; CD spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	antimicrobial peptides NMR spectroscopy bee venom CD spectroscopy hemolytic activity
http://linked.open...ontrolniKodProRIV	[8ED9C850AA8E]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Munich, The Hague, Berlin, Vienna, Brussels
http://linked.open...atelePatentuVzoru	Evropský patentový úřad
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Antimicrobial peptides from insects for possible therapeutic applications
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Borovičková, Lenka Cvačka, Josef Fučík, Vladimír Monincová, Lenka Slaninová, Jiřina Čeřovský, Václav Hovorka, Oldřich Voburka, Zdeněk
http://linked.open...mniOchranaPatentu	A - EPO (Evropský patentový úřad)
http://linked.open...avai/riv/vlastnik	Ústav organické chemie a biochemie Akademie věd ČR, v. v. i
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
http://linked.open...stnikPatentuVzoru	Ústav organické chemie a biochemie Akademie věd ČR, v. v. i

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