About: Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin

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About: Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) is a natural biologically active substance with antioxidant activity. The ability of curcumin to inhibit free radical reactions can be used in the prevention of diseases such as cancer and coronary heart disease. UV-Vis spectrophotometric and chemiluminescent dynamic methods for determination of the antioxidant activity of curcumin were developed. The spectrophotometric method includes investigation of the interaction between DNA, isolated from HL-60 cells, and curcumin. The decreasing absorption of curcumin in the presence of HL-60 DNA against the blank sample can be a measurement for some complex formation between curcumin and DNA. The chemiluminescent method involves three tests for the detection of luminol- dependent chemiluminescence based on model systems that generate superoxide, hydroxide and hypochlorite radicals. The strongest decay of chemilunimescence was registered at the highest concentration of curcumin (100 mu mol L-1). Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) is a natural biologically active substance with antioxidant activity. The ability of curcumin to inhibit free radical reactions can be used in the prevention of diseases such as cancer and coronary heart disease. UV-Vis spectrophotometric and chemiluminescent dynamic methods for determination of the antioxidant activity of curcumin were developed. The spectrophotometric method includes investigation of the interaction between DNA, isolated from HL-60 cells, and curcumin. The decreasing absorption of curcumin in the presence of HL-60 DNA against the blank sample can be a measurement for some complex formation between curcumin and DNA. The chemiluminescent method involves three tests for the detection of luminol- dependent chemiluminescence based on model systems that generate superoxide, hydroxide and hypochlorite radicals. The strongest decay of chemilunimescence was registered at the highest concentration of curcumin (100 mu mol L-1). (en)
Title	Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin (en)
skos:prefLabel	Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin Application of UV-Vis spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin (en)
skos:notation	RIV/61388963:_____/12:00383640!RIV13-AV0-61388963
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Stanchev, Stancho
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	123430
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/12:00383640
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	curcumin; antioxidant; UV-Vis spectrophotometry; DNA complexation; chemiluminescence (en)
http://linked.open.../riv/klicoveSlovo	chemiluminescence DNA complexation UV-Vis spectrophotometry curcumin antioxidant
http://linked.open...odStatuVydavatele	RS - Srbská republika
http://linked.open...ontrolniKodProRIV	[0F0EBAD6A37E]
http://linked.open...i/riv/nazevZdroje	Journal of the Serbian Chemical Society
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	77
http://linked.open...iv/tvurceVysledku	Hadjimitova, V. Konstantinov, S. Obreshkova, D. Pencheva, I. Stanchev, Stancho
http://linked.open...ain/vavai/riv/wos	000308830900008
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0352-5139
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.2298/JSC110621032S

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