About: Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p

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About: Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The genes APR1 and CPY1 of the pathogenic yeast Candida albicans encode vacuolar aspartic protease and serine carboxypeptidase, respectively. Transcription of both APR1 and CPY1 was upregulated in mid-exponential phase, together with increasing size of the vacuoles, when C. albicans was cultivated in a rich medium at 30 °C. However, simultaneous up-regulation of protein synthesis occurred only for Cpy1p. Analysis of APR1 and CPY1 expression under nitrogen limited conditions revealed, that the genes were regulated on both the transcriptional and translational level and detectable amounts of Apr1p were synthesized only when C. albicans was grown in nitrogen limited media. The genes APR1 and CPY1 of the pathogenic yeast Candida albicans encode vacuolar aspartic protease and serine carboxypeptidase, respectively. Transcription of both APR1 and CPY1 was upregulated in mid-exponential phase, together with increasing size of the vacuoles, when C. albicans was cultivated in a rich medium at 30 °C. However, simultaneous up-regulation of protein synthesis occurred only for Cpy1p. Analysis of APR1 and CPY1 expression under nitrogen limited conditions revealed, that the genes were regulated on both the transcriptional and translational level and detectable amounts of Apr1p were synthesized only when C. albicans was grown in nitrogen limited media. (en)
Title	Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p (en)
skos:prefLabel	Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p (en)
skos:notation	RIV/61388963:_____/12:00379073!RIV13-AV0-61388963
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/09/1945), P(LC531), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Pichová, Iva Hrušková, Olga Bauerová, Václava
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	154253
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/12:00379073
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Candida albicans; carboxypeptidase Y; nitrogen starvation; vacuole (en)
http://linked.open.../riv/klicoveSlovo	vacuole Candida albicans carboxypeptidase Y nitrogen starvation
http://linked.open...odStatuVydavatele	CA - Kanada
http://linked.open...ontrolniKodProRIV	[BBB2DDDECFFE]
http://linked.open...i/riv/nazevZdroje	Canadian Journal of Microbiology
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of aspartic proteinases in nutrient acquisition and starvation of pathogenic yeasts Candida albicans and Candida parapsilosis Centre on molecular biology and physiology of yeast communities
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	58
http://linked.open...iv/tvurceVysledku	Pichová, Iva Hrušková, Olga Bauerová, Václava
http://linked.open...ain/vavai/riv/wos	000303659500015
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0008-4166
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1139/W2012-030

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