About: An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids     Goto   Sponge   NotDistinct   Permalink

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Description
  • Polysubstituted pyrimidinylphosphonic and 1,3,5-triazinylphosphonic acids with potential biological properties were prepared in high yields by the microwave-assisted Michaelis-Arbuzov reaction of trialkyl phosphite with the corresponding halopyrimidines and halo-1,3,5-triazines, respectively, followed by the standard deprotection of the phosphonate group using TMSBr in acetonitrile.
  • Polysubstituted pyrimidinylphosphonic and 1,3,5-triazinylphosphonic acids with potential biological properties were prepared in high yields by the microwave-assisted Michaelis-Arbuzov reaction of trialkyl phosphite with the corresponding halopyrimidines and halo-1,3,5-triazines, respectively, followed by the standard deprotection of the phosphonate group using TMSBr in acetonitrile. (en)
Title
  • An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids
  • An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids (en)
skos:prefLabel
  • An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids
  • An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids (en)
skos:notation
  • RIV/61388963:_____/12:00377689!RIV13-AV0-61388963
http://linked.open...avai/riv/aktivita
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  • P(1M0508), P(KJB400550903), Z(AV0Z40550506)
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  • 3
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  • 121929
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  • RIV/61388963:_____/12:00377689
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  • phosphonic acids; pyrimidines; 1,3,5-triazines; microwave-assisted synthesis; influenza virus (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [E4AE17763CF4]
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  • Tetrahedron
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  • 68
http://linked.open...iv/tvurceVysledku
  • Balzarini, J.
  • Baszczyňski, Ondřej
  • Dračínský, Martin
  • Holý, Antonín
  • Janeba, Zlatko
  • Jansa, Petr
  • Klepetářová, Blanka
  • Hradil, Ondřej
http://linked.open...ain/vavai/riv/wos
  • 000299609300010
http://linked.open...n/vavai/riv/zamer
issn
  • 0040-4020
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.tet.2011.11.040
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