About: Novel substituted 9-norbornylpurines and their activities against RNA viruses

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We report on the synthesis and the study of the structure-activity relationship of novel 9-norbornyl-6-chloropurine derivatives, which exert selective antiviral activity on the replication of Coxsackievirus B3. In particular, the synthetic approaches towards norbornyl derivatives bearing diverse side chains were studied. We report on the synthesis and the study of the structure-activity relationship of novel 9-norbornyl-6-chloropurine derivatives, which exert selective antiviral activity on the replication of Coxsackievirus B3. In particular, the synthetic approaches towards norbornyl derivatives bearing diverse side chains were studied. (en)
Title	Novel substituted 9-norbornylpurines and their activities against RNA viruses Novel substituted 9-norbornylpurines and their activities against RNA viruses (en)
skos:prefLabel	Novel substituted 9-norbornylpurines and their activities against RNA viruses Novel substituted 9-norbornylpurines and their activities against RNA viruses (en)
skos:notation	RIV/61388963:_____/12:00376440!RIV13-AV0-61388963
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0508), P(GAP303/11/1297), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Dračínský, Martin Hřebabecký, Hubert Nencka, Radim Dejmek, Milan Šála, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	154813
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/12:00376440
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antiviral; coxsackievirus; norbornane; picornaviruses; purine (en)
http://linked.open.../riv/klicoveSlovo	purine coxsackievirus norbornane picornaviruses antiviral
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[8AF3C9BB7453]
http://linked.open...i/riv/nazevZdroje	Bioorganic and Medicinal Chemistry Letters
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of antiviral and cytostatic effects of novel carbocyclic nucleoside analogs New Antivirals and Antineoplastics
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Dračínský, Martin Dejmek, Milan Hřebabecký, Hubert Leyssen, P. Nencka, Radim Neyts, J. Šála, Michal De Palma, A. M.
http://linked.open...ain/vavai/riv/wos	000300451200026
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0960-894X
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.bmcl.2012.01.040

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