About: [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha, omega-Diynes     Goto   Sponge   NotDistinct   Permalink

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  • 6-Alkynyl-7-benzylpurines were prepared by the Sonogashira reaction from 6-chloro-7-benzylpurines and terminal alkynes. The prepared alkynylpurines were cyclotrimerized with various 1,6-diynes in the presence of Ni(cod)2/2PPh3 catalytic system into the corresponding 6-aryl-7-benzylpurines under ambient conditions. The prepared 6-alkynyl- and 6-aryl-7-benzylpurines were tested for cytostatic activity.
  • 6-Alkynyl-7-benzylpurines were prepared by the Sonogashira reaction from 6-chloro-7-benzylpurines and terminal alkynes. The prepared alkynylpurines were cyclotrimerized with various 1,6-diynes in the presence of Ni(cod)2/2PPh3 catalytic system into the corresponding 6-aryl-7-benzylpurines under ambient conditions. The prepared 6-alkynyl- and 6-aryl-7-benzylpurines were tested for cytostatic activity. (en)
Title
  • [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha, omega-Diynes
  • [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha, omega-Diynes (en)
skos:prefLabel
  • [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha, omega-Diynes
  • [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha, omega-Diynes (en)
skos:notation
  • RIV/61388963:_____/10:00356369!RIV11-MSM-61388963
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0508), S, Z(AV0Z40550506), Z(MSM0021620857)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 300922
http://linked.open...ai/riv/idVysledku
  • RIV/61388963:_____/10:00356369
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cyclotrimerization; purine; alkyne; nickel; catalysis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • JP - Japonsko
http://linked.open...ontrolniKodProRIV
  • [901F122A0BC2]
http://linked.open...i/riv/nazevZdroje
  • Heterocycles
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 82
http://linked.open...iv/tvurceVysledku
  • Hocek, Michal
  • Pohl, Radek
  • Votruba, Ivan
  • Klepetářová, Blanka
  • Kotora, M.
  • Opekar, S.
  • Turek, P.
http://linked.open...ain/vavai/riv/wos
  • 000286906100065
http://linked.open...n/vavai/riv/zamer
issn
  • 0385-5414
number of pages
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