About: Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC

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About: Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A traditional mastic named yakı sakızı prepared from the roots of Scorzonera latifolia DC. is used as a folk remedy for treatment of pain in Turkish folk medicine. The extract of the S. latifolia roots was prepared and subjected to isolation procedures. Writhing and tail-flick tests were used to determine the antinociceptive activity. The n-hexane fraction of the S. latifolia root methanolic extract showed potent antinociceptiveactivity in both writhing and tail-flick tests. Three compounds were isolated using bioassay-guided chromatographic purification. Isolated compounds were triterpene taraxasteryl myristate, taraxasteryl acetate, and fern-7-en-3-b-one, structures were elucidated by means of MS and NMR techniques. Both taraxasterol derivatives showed promising antinociceptive activity when compared to reference compounds. The root extract and the isolated compounds showed promising antinociceptive activities. A traditional mastic named yakı sakızı prepared from the roots of Scorzonera latifolia DC. is used as a folk remedy for treatment of pain in Turkish folk medicine. The extract of the S. latifolia roots was prepared and subjected to isolation procedures. Writhing and tail-flick tests were used to determine the antinociceptive activity. The n-hexane fraction of the S. latifolia root methanolic extract showed potent antinociceptiveactivity in both writhing and tail-flick tests. Three compounds were isolated using bioassay-guided chromatographic purification. Isolated compounds were triterpene taraxasteryl myristate, taraxasteryl acetate, and fern-7-en-3-b-one, structures were elucidated by means of MS and NMR techniques. Both taraxasterol derivatives showed promising antinociceptive activity when compared to reference compounds. The root extract and the isolated compounds showed promising antinociceptive activities. (en)
Title	Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC (en)
skos:prefLabel	Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC Analgesic compounds from Scorzonera latifolia (Fisch. and Mey.) DC (en)
skos:notation	RIV/61388963:_____/10:00352143!RIV11-AV0-61388963
http://linked.open...avai/riv/aktivita	S V Z
http://linked.open...avai/riv/aktivity	S, V, Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Cvačka, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	246296
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/10:00352143
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Scorzonera latifolia; analgesic activity; triterpenes (en)
http://linked.open.../riv/klicoveSlovo	Scorzonera latifolia triterpenes analgesic activity
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[38C76C2971F2]
http://linked.open...i/riv/nazevZdroje	Journal of Ethnopharmacology
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	131
http://linked.open...iv/tvurceVysledku	Cvačka, Josef Šmejkal, K. Žemlička, M. Bahadir, Ö. Citoglu, G. S. Dall Acqua, S. Özbek, H.
http://linked.open...ain/vavai/riv/wos	000281325500011
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0378-8741
number of pages	5 (xsd:int)

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