About: Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position

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About: Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A series of 6-alkyl derivatives of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine (HPMP-5-azaC) was prepared using ammonia mediated ring-opening reaction of diisopropyl esters of HPMP-5-azaC to a corresponding carbamoylguanidine derivative followed by ring-closure reaction with orthoesters. A series of 6-alkyl derivatives of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine (HPMP-5-azaC) was prepared using ammonia mediated ring-opening reaction of diisopropyl esters of HPMP-5-azaC to a corresponding carbamoylguanidine derivative followed by ring-closure reaction with orthoesters. (en)
Title	Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position (en)
skos:prefLabel	Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position (en)
skos:notation	RIV/61388963:_____/10:00342431!RIV11-MSM-61388963
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0508), P(1QS400550501), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Krečmerová, Marcela Holý, Antonín Masojídková, Milena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	245325
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/10:00342431
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	5-azacytosine; acyclic nucleoside phosphonates; antivirals; orthoesters; condensation (en)
http://linked.open.../riv/klicoveSlovo	antivirals acyclic nucleoside phosphonates condensation orthoesters 5-azacytosine
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B2C2BFACF332]
http://linked.open...i/riv/nazevZdroje	Bioorganic & Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	New Antivirals and Antineoplastics Novel antivirals and antineoplastics
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Holý, Antonín Krečmerová, Marcela Masojídková, Milena
http://linked.open...ain/vavai/riv/wos	000272892100042
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0968-0896
number of pages	9 (xsd:int)

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