About: The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus

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About: The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In the present work we focus on the contribution of NC to the oligomerization of CA leading to assembly of Mason-Pfizer monkey virus (M-PMV) and HIV-1. Analyzing in vitro assembly of substitution and deletion mutants of .delta.ProCANC we identified a “spacer-like sequence (NC15) at the M-PMV NC N-terminus. This NC15 domain is indispensable for the assembly and cannot be substituted with oligomerization domains of GCN4 or CREB proteins. In the present work we focus on the contribution of NC to the oligomerization of CA leading to assembly of Mason-Pfizer monkey virus (M-PMV) and HIV-1. Analyzing in vitro assembly of substitution and deletion mutants of .delta.ProCANC we identified a “spacer-like sequence (NC15) at the M-PMV NC N-terminus. This NC15 domain is indispensable for the assembly and cannot be substituted with oligomerization domains of GCN4 or CREB proteins. (en)
Title	The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus (en)
skos:prefLabel	The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus (en)
skos:notation	RIV/61388963:_____/10:00342386!RIV11-GA0-61388963
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0508), P(GA204/09/1388), P(ME 904), Z(AV0Z40550506), Z(MSM6046137305)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Böhmová, Karolína Pichová, Iva Štokrová, Jitka Rumlová, Michaela Hadravová, Romana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	255952
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/10:00342386
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mason-Pfizer Monkey Virus; Human Immunodeficiency Virus; assembly; NC (en)
http://linked.open.../riv/klicoveSlovo	assembly Human Immunodeficiency Virus Mason-Pfizer Monkey Virus NC
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2617C944F3A7]
http://linked.open...i/riv/nazevZdroje	Journal of Virology
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20904 New Antivirals and Antineoplastics Characterization of novel host cell protein interacting with protease of Mason-Pfizer monkey virus
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	84
http://linked.open...iv/tvurceVysledku	Pichová, Iva Ruml, T. Štokrová, Jitka Rumlová, Michaela Hadravová, Romana Böhmová, Karolína Tůma, R.
http://linked.open...ain/vavai/riv/wos	000273853200032
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Teoretické základy potravinářských a biochemických technologií
issn	0022-538X
number of pages	12 (xsd:int)

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