About: Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species

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About: Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Adefovir (9-(2-fosfonomethoxyethyl)adenin) je acyklický fosfonát nukleosidu užívaný v praxi pro léčbu hetatitidy B. Cílem této studie bylo stanovení vlivu aktivátoru průniku DDAK (dodecyl ester 6-dimethylaminohexanové kyseliny) na transdermální a topickou aplikaci adefoviru. (cs) Adefovir (9-(2-phosphonomethoxyethyl)adenine) is an acyclic nucleoside phosphonate currently used for the treatment of hepatitis B. The aim of this study was to evaluate the effect of permeation enhancer DDAK (6-dimethylaminohaxanoic acid dodecyl ester) on the transdermal and topical delivery of adefovir. Adefovir (9-(2-phosphonomethoxyethyl)adenine) is an acyclic nucleoside phosphonate currently used for the treatment of hepatitis B. The aim of this study was to evaluate the effect of permeation enhancer DDAK (6-dimethylaminohaxanoic acid dodecyl ester) on the transdermal and topical delivery of adefovir. (en)
Title	Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species (en) Aktivátor průniku dodecycl 6-(dimethylamino)hexanoát zlepšuje transdermální a topickou aplikaci adefoviru: Vliv pH, párování iontů a druhu kůže (cs)
skos:prefLabel	Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species Permeation enhancer dedocyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: Influence of pH, ion-pairing and skin species (en) Aktivátor průniku dodecycl 6-(dimethylamino)hexanoát zlepšuje transdermální a topickou aplikaci adefoviru: Vliv pH, párování iontů a druhu kůže (cs)
skos:notation	RIV/61388963:_____/08:00314920!RIV09-AV0-61388963
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(1M0508), S, Z(AV0Z40550506), Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Holý, Antonín
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	386302
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/08:00314920
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adefovir; acyclic nucleoside phosphonates; antiviral; transdermal drug delivery; permeation enhancer (en)
http://linked.open.../riv/klicoveSlovo	permeation enhancer antiviral acyclic nucleoside phosphonates transdermal drug delivery adefovir
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[BE3670DACAF7]
http://linked.open...i/riv/nazevZdroje	European Journal of Pharmaceutics and Biopharmaceutics
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	New Antivirals and Antineoplastics
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	70
http://linked.open...iv/tvurceVysledku	Holý, Antonín Novotný, J. Vávrová, K. Hrabálek, A. Lorencová, K.
http://linked.open...ain/vavai/riv/wos	000261484300028
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Research of new drug structures
issn	0939-6411
number of pages	7 (xsd:int)

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