About: Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-couplin     Goto   Sponge   NotDistinct   Permalink

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Description
  • 8-Allyl-, cyclopropyl-, trifluoromethyl-, cyano-, carbethoxy- and acetaldehydo-2,6-diamino- 9-[2-(phosphonomethoxy)ethyl]purine (PMEDAP) were prepared by Negishi cross-coupling of the 8-bromo-PMEDAP under catalysis with Pd2dba3 with various phosphine ligands followed by deprotection.
  • 8-Allyl-, cyclopropyl-, trifluoromethyl-, cyano-, carbethoxy- and acetaldehydo-2,6-diamino- 9-[2-(phosphonomethoxy)ethyl]purine (PMEDAP) were prepared by Negishi cross-coupling of the 8-bromo-PMEDAP under catalysis with Pd2dba3 with various phosphine ligands followed by deprotection. (en)
  • 8-Allyl-, cyklopropyl-, trifluoromethyl-, kyano-, karbethoxy- and acetaldehydo-2,6-diamino- 9-[2-(fosfonomethoxy)ethyl]purin (PMEDAP) byly připraveny pomocí Negishiho cross-couplingu z 8-brom-PMEDAPu za katalýzy Pd2dba3 s různými fosfinovými ligandy a jeho následnou deprotekcí. (cs)
Title
  • Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-couplin
  • Příprava 8-C-substituovaných acyklických nukleosidfosfonátů odvozených od 2,6 diaminopurinu s využitím Negishiho cross-couplingu (cs)
  • Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-couplin (en)
skos:prefLabel
  • Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-couplin
  • Příprava 8-C-substituovaných acyklických nukleosidfosfonátů odvozených od 2,6 diaminopurinu s využitím Negishiho cross-couplingu (cs)
  • Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-couplin (en)
skos:notation
  • RIV/61388963:_____/08:00310044!RIV09-AV0-61388963
http://linked.open...avai/riv/aktivita
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  • P(1M0508), P(1QS400550501), Z(AV0Z40550506)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 398812
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  • RIV/61388963:_____/08:00310044
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  • 8-C-substituted; Negishi cross-coupling; acyclic nucleoside phosphonates; 2,6-diaminopurine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [839B1F879B45]
http://linked.open...v/mistoKonaniAkce
  • Český Krumlov
http://linked.open...i/riv/mistoVydani
  • Praha
http://linked.open...i/riv/nazevZdroje
  • Chemistry of Nucleic Acid Components
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
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http://linked.open...iv/tvurceVysledku
  • Holý, Antonín
  • Pohl, Radek
  • Sedláček, Ondřej
http://linked.open...vavai/riv/typAkce
http://linked.open...ain/vavai/riv/wos
  • 000257885700110
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Institute of Organic Chemistry and Biochemistry ASCR
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  • 978-80-86241-29-6
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